Matches in DBpedia 2014 for { <http://dbpedia.org/resource/MAP3K7IP3> ?p ?o. }
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- MAP3K7IP3 abstract "Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 is an enzyme that in humans is encoded by the MAP3K7IP3 gene.The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.".
- MAP3K7IP3 entrezgene "257397".
- MAP3K7IP3 wikiPageID "15214447".
- MAP3K7IP3 wikiPageRevisionID "592357379".
- MAP3K7IP3 hasPhotoCollection MAP3K7IP3.
- MAP3K7IP3 requireManualInspection "no".
- MAP3K7IP3 summaryText "The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.".
- MAP3K7IP3 updateCitations "yes".
- MAP3K7IP3 updatePage "yes".
- MAP3K7IP3 updateProteinBox "yes".
- MAP3K7IP3 updateSummary "yes".
- MAP3K7IP3 type Biomolecule.
- MAP3K7IP3 type Protein.
- MAP3K7IP3 type BiologicalObject.
- MAP3K7IP3 comment "Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 is an enzyme that in humans is encoded by the MAP3K7IP3 gene.The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1.".
- MAP3K7IP3 label "MAP3K7IP3".
- MAP3K7IP3 sameAs m.03hm2s9.
- MAP3K7IP3 sameAs Q6714374.
- MAP3K7IP3 sameAs Q6714374.
- MAP3K7IP3 wasDerivedFrom MAP3K7IP3?oldid=592357379.
- MAP3K7IP3 isPrimaryTopicOf MAP3K7IP3.