Matches in DBpedia 2014 for { <http://dbpedia.org/resource/MAPK14> ?p ?o. }
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- MAPK14 abstract "Mitogen-activated protein kinase 14, also called p38-α, is an enzyme that in humans is encoded by the MAPK14 gene.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress-related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.".
- MAPK14 entrezgene "1432".
- MAPK14 wikiPageExternalLink www.mapkinases.eu.
- MAPK14 wikiPageID "13570754".
- MAPK14 wikiPageRevisionID "592357697".
- MAPK14 hasPhotoCollection MAPK14.
- MAPK14 requireManualInspection "no".
- MAPK14 summaryText "The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases , or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress-related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.".
- MAPK14 updateCitations "yes".
- MAPK14 updatePage "yes".
- MAPK14 updateProteinBox "yes".
- MAPK14 updateSummary "yes".
- MAPK14 type Biomolecule.
- MAPK14 type Protein.
- MAPK14 type BiologicalObject.
- MAPK14 comment "Mitogen-activated protein kinase 14, also called p38-α, is an enzyme that in humans is encoded by the MAPK14 gene.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines.".
- MAPK14 label "MAPK14".
- MAPK14 label "MAPK14".
- MAPK14 sameAs MAPK14.
- MAPK14 sameAs MAPK14.
- MAPK14 sameAs m.03c9q92.
- MAPK14 sameAs Q6714402.
- MAPK14 sameAs Q6714402.
- MAPK14 sameAs 1540.
- MAPK14 sameAs 3533.
- MAPK14 wasDerivedFrom MAPK14?oldid=592357697.
- MAPK14 isPrimaryTopicOf MAPK14.