Matches in DBpedia 2014 for { <http://dbpedia.org/resource/MAPK8IP1> ?p ?o. }
Showing items 1 to 22 of
22
with 100 items per page.
- MAPK8IP1 abstract "C-jun-amino-terminal kinase-interacting protein 1 is an enzyme that in humans is encoded by the MAPK8IP1 gene.The protein encoded by this gene is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.".
- MAPK8IP1 entrezgene "9479".
- MAPK8IP1 wikiPageID "14156520".
- MAPK8IP1 wikiPageRevisionID "592357845".
- MAPK8IP1 hasPhotoCollection MAPK8IP1.
- MAPK8IP1 requireManualInspection "no".
- MAPK8IP1 summaryText "The protein encoded by this gene is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase . This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.".
- MAPK8IP1 updateCitations "yes".
- MAPK8IP1 updatePage "yes".
- MAPK8IP1 updateProteinBox "yes".
- MAPK8IP1 updateSummary "yes".
- MAPK8IP1 type Biomolecule.
- MAPK8IP1 type Protein.
- MAPK8IP1 type BiologicalObject.
- MAPK8IP1 comment "C-jun-amino-terminal kinase-interacting protein 1 is an enzyme that in humans is encoded by the MAPK8IP1 gene.The protein encoded by this gene is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells.".
- MAPK8IP1 label "MAPK8IP1".
- MAPK8IP1 sameAs m.03cw8xh.
- MAPK8IP1 sameAs Q15996784.
- MAPK8IP1 sameAs Q15996784.
- MAPK8IP1 sameAs MAPK8IP1.
- MAPK8IP1 wasDerivedFrom MAPK8IP1?oldid=592357845.
- MAPK8IP1 isPrimaryTopicOf MAPK8IP1.