Matches in DBpedia 2014 for { <http://dbpedia.org/resource/MBNL1> ?p ?o. }
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- MBNL1 abstract "Muscleblind-like (Drosophila), also known as MBNL1, is a protein that in humans is encoded by the MBNL1 gene. It has been implicated in Myotonic dystrophy and has been shown to autoregulate its transcript.Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU(U/G)Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues (http://www.uniprot.org/uniprot/Q9NR56)".
- MBNL1 entrezgene "4154".
- MBNL1 wikiPageExternalLink Q9NR56).
- MBNL1 wikiPageID "14874568".
- MBNL1 wikiPageRevisionID "592459633".
- MBNL1 hasPhotoCollection MBNL1.
- MBNL1 requireManualInspection "no".
- MBNL1 updateCitations "no".
- MBNL1 updatePage "yes".
- MBNL1 updateProteinBox "yes".
- MBNL1 updateSummary "yes".
- MBNL1 type Biomolecule.
- MBNL1 type Protein.
- MBNL1 type BiologicalObject.
- MBNL1 comment "Muscleblind-like (Drosophila), also known as MBNL1, is a protein that in humans is encoded by the MBNL1 gene. It has been implicated in Myotonic dystrophy and has been shown to autoregulate its transcript.Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle.".
- MBNL1 label "MBNL1".
- MBNL1 sameAs m.03g_th4.
- MBNL1 sameAs Q6714740.
- MBNL1 sameAs Q6714740.
- MBNL1 wasDerivedFrom MBNL1?oldid=592459633.
- MBNL1 isPrimaryTopicOf MBNL1.