Matches in DBpedia 2014 for { <http://dbpedia.org/resource/MDC1> ?p ?o. }
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- MDC1 abstract "Mediator of DNA damage checkpoint protein 1 is a protein that in humans is encoded by the MDC1 gene.The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.".
- MDC1 entrezgene "9656".
- MDC1 wikiPageID "14761654".
- MDC1 wikiPageRevisionID "592461261".
- MDC1 hasPhotoCollection MDC1.
- MDC1 requireManualInspection "no".
- MDC1 summaryText "The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.".
- MDC1 updateCitations "yes".
- MDC1 updatePage "yes".
- MDC1 updateProteinBox "yes".
- MDC1 updateSummary "yes".
- MDC1 type Biomolecule.
- MDC1 type Protein.
- MDC1 type BiologicalObject.
- MDC1 comment "Mediator of DNA damage checkpoint protein 1 is a protein that in humans is encoded by the MDC1 gene.The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage.".
- MDC1 label "MDC1".
- MDC1 sameAs m.03gx28n.
- MDC1 sameAs Q6715130.
- MDC1 sameAs Q6715130.
- MDC1 wasDerivedFrom MDC1?oldid=592461261.
- MDC1 isPrimaryTopicOf MDC1.