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- MEFV abstract "MEFV (Mediterranean fever) is a human gene that provides instructions for making a protein called pyrin (also known as marenostrin). Pyrin is produced in certain white blood cells (neutrophils, eosinophils and monocytes) that play a role in inflammation and in fighting infection. Inside these white blood cells, pyrin is found with the cytoskeleton, the structural framework that helps to define the shape, size, and movement of a cell. Pyrin's protein structure also allows it to interact with other molecules involved in fighting infection and in the inflammatory response.Although pyrin's function is not fully understood, it likely assists in keeping the inflammation process under control. Research indicates that pyrin helps regulate inflammation by interacting with the cytoskeleton. Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed.The MEFV gene is located on the short (p) arm of chromosome 16 at position 13.3, from base pair 3,292,027 to 3,306,626.".
- MEFV entrezgene "4210".
- MEFV wikiPageID "3508854".
- MEFV wikiPageRevisionID "601242743".
- MEFV hasPhotoCollection MEFV.
- MEFV requireManualInspection "no".
- MEFV updateCitations "no".
- MEFV updatePage "yes".
- MEFV updateProteinBox "yes".
- MEFV updateSummary "no".
- MEFV type Biomolecule.
- MEFV type Protein.
- MEFV type BiologicalObject.
- MEFV comment "MEFV (Mediterranean fever) is a human gene that provides instructions for making a protein called pyrin (also known as marenostrin). Pyrin is produced in certain white blood cells (neutrophils, eosinophils and monocytes) that play a role in inflammation and in fighting infection. Inside these white blood cells, pyrin is found with the cytoskeleton, the structural framework that helps to define the shape, size, and movement of a cell.".
- MEFV label "Fiebre mediterranea familiar".
- MEFV label "MEFV".
- MEFV sameAs Fiebre_mediterranea_familiar.
- MEFV sameAs MEFV.
- MEFV sameAs m.09hc5_.
- MEFV sameAs Q11681842.
- MEFV sameAs Q11681842.
- MEFV sameAs MEFV.
- MEFV sameAs 962.
- MEFV wasDerivedFrom MEFV?oldid=601242743.
- MEFV isPrimaryTopicOf MEFV.