Matches in DBpedia 2014 for { <http://dbpedia.org/resource/MMP25> ?p ?o. }
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- MMP25 abstract "Matrix metalloproteinase-25 is an enzyme that in humans is encoded by the MMP25 gene.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.".
- MMP25 entrezgene "64386".
- MMP25 wikiPageExternalLink merops.cgi?id=M10.024.
- MMP25 wikiPageID "14878547".
- MMP25 wikiPageRevisionID "592523810".
- MMP25 hasPhotoCollection MMP25.
- MMP25 requireManualInspection "no".
- MMP25 summaryText "Proteins of the matrix metalloproteinase family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.".
- MMP25 updateCitations "yes".
- MMP25 updatePage "yes".
- MMP25 updateProteinBox "yes".
- MMP25 updateSummary "yes".
- MMP25 type Biomolecule.
- MMP25 type Protein.
- MMP25 type BiologicalObject.
- MMP25 comment "Matrix metalloproteinase-25 is an enzyme that in humans is encoded by the MMP25 gene.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.".
- MMP25 label "MMP25".
- MMP25 sameAs m.03h00y8.
- MMP25 sameAs Q6716823.
- MMP25 sameAs Q6716823.
- MMP25 wasDerivedFrom MMP25?oldid=592523810.
- MMP25 isPrimaryTopicOf MMP25.