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- MTORC1 abstract "mTORC1, also known as mammalian target of rapamycin complex 1 or mechanistic target of rapamycin complex 1, is a protein complex that functions as a nutrient/energy/redox sensor and controls protein synthesis.mTOR Complex 1 (mTORC1) is composed of mTOR itself, regulatory-associated protein of mTOR (Raptor), mammalian lethal with SEC13 protein 8 (MLST8) and the recently identified PRAS40 and DEPTOR. This complex embodies the classic functions of mTOR, namely as a nutrient/energy/redox sensor and controller of protein synthesis. The activity of this complex is controlled by insulin, growth factors, amino acids (particularly leucine), and oxidative stress.The role of mTORC1 is to activate translation of proteins. In order for cells to grow and proliferate by manufacturing more proteins, the cells must ensure that they have the resources available for protein production. Thus, for protein production, and therefore mTORC1 activation, cells must have adequate energy resources, nutrient availability, oxygen abundance, and proper growth factors in order for protein translation to begin.".
- MTORC1 arm "p".
- MTORC1 band "36".
- MTORC1 chromosome "1".
- MTORC1 ecNumber "2.7.11.1".
- MTORC1 entrezgene "2475".
- MTORC1 hgncid "3942".
- MTORC1 omim "601231".
- MTORC1 refseq "NM_004958".
- MTORC1 symbol "FRAP, FRAP2, FRAP1".
- MTORC1 symbol "MTOR".
- MTORC1 thumbnail Activation_of_mTORC1_at_the_Lysosome.jpg?width=300.
- MTORC1 uniprot "P42345".
- MTORC1 wikiPageID "38402739".
- MTORC1 wikiPageRevisionID "597684588".
- MTORC1 altsymbols "FRAP, FRAP2, FRAP1".
- MTORC1 arm "p".
- MTORC1 band "36".
- MTORC1 chromosome "1".
- MTORC1 ecnumber "2.7".
- MTORC1 entrezgene "2475".
- MTORC1 hasPhotoCollection MTORC1.
- MTORC1 hgncid "3942".
- MTORC1 name Mammalian_target_of_rapamycin.
- MTORC1 omim "601231".
- MTORC1 refseq "NM_004958".
- MTORC1 symbol Mammalian_target_of_rapamycin.
- MTORC1 uniprot "P42345".
- MTORC1 subject Category:EC_2.7.11.
- MTORC1 subject Category:Human_proteins.
- MTORC1 subject Category:Signal_transduction.
- MTORC1 subject Category:Tor_signaling_pathway.
- MTORC1 type Biomolecule.
- MTORC1 type Protein.
- MTORC1 type BiologicalObject.
- MTORC1 comment "mTORC1, also known as mammalian target of rapamycin complex 1 or mechanistic target of rapamycin complex 1, is a protein complex that functions as a nutrient/energy/redox sensor and controls protein synthesis.mTOR Complex 1 (mTORC1) is composed of mTOR itself, regulatory-associated protein of mTOR (Raptor), mammalian lethal with SEC13 protein 8 (MLST8) and the recently identified PRAS40 and DEPTOR.".
- MTORC1 label "MTORC1".
- MTORC1 sameAs m.0qfn3vw.
- MTORC1 sameAs Q6718498.
- MTORC1 sameAs Q6718498.
- MTORC1 wasDerivedFrom MTORC1?oldid=597684588.
- MTORC1 depiction Activation_of_mTORC1_at_the_Lysosome.jpg.
- MTORC1 isPrimaryTopicOf MTORC1.
- MTORC1 name "mTOR".