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- Macromolecular_crowding abstract "The phenomenon of macromolecular crowding alters the properties of molecules in a solution when high concentrations of macromolecules such as proteins are present. Such conditions occur routinely in living cells; for instance, the cytosol of Escherichia coli contains about 300–400 mg/mL of macromolecules. Crowding occurs since these high concentrations of macromolecules reduce the volume of solvent available for other molecules in the solution, which has the result of increasing their effective concentrations. This crowding effect can make molecules in cells behave in radically different ways than in test-tube assays. Consequently, measurements of the properties of enzymes or processes in metabolism that are made in the laboratory (in vitro) in dilute solutions may be different by many orders of magnitude from the true values seen in living cells (in vivo). The study of biochemical processes under realistically crowded conditions is very important, since these conditions are a ubiquitous property of all cells and crowding may be essential for the efficient operation of metabolism.".
- Macromolecular_crowding thumbnail Crowded_cytosol.png?width=300.
- Macromolecular_crowding wikiPageExternalLink 7400056.html.
- Macromolecular_crowding wikiPageID "19248693".
- Macromolecular_crowding wikiPageRevisionID "592335105".
- Macromolecular_crowding hasPhotoCollection Macromolecular_crowding.
- Macromolecular_crowding subject Category:Biophysics.
- Macromolecular_crowding subject Category:Physical_chemistry.
- Macromolecular_crowding subject Category:Protein_methods.
- Macromolecular_crowding subject Category:Solutions.
- Macromolecular_crowding type Ability105616246.
- Macromolecular_crowding type Abstraction100002137.
- Macromolecular_crowding type Cognition100023271.
- Macromolecular_crowding type Know-how105616786.
- Macromolecular_crowding type Matter100020827.
- Macromolecular_crowding type Method105660268.
- Macromolecular_crowding type Mixture114586258.
- Macromolecular_crowding type Part113809207.
- Macromolecular_crowding type PhysicalEntity100001930.
- Macromolecular_crowding type ProteinMethods.
- Macromolecular_crowding type PsychologicalFeature100023100.
- Macromolecular_crowding type Relation100031921.
- Macromolecular_crowding type Solution114589223.
- Macromolecular_crowding type Solutions.
- Macromolecular_crowding type Substance100019613.
- Macromolecular_crowding comment "The phenomenon of macromolecular crowding alters the properties of molecules in a solution when high concentrations of macromolecules such as proteins are present. Such conditions occur routinely in living cells; for instance, the cytosol of Escherichia coli contains about 300–400 mg/mL of macromolecules.".
- Macromolecular_crowding label "Macromolecular crowding".
- Macromolecular_crowding label "分子クラウディング".
- Macromolecular_crowding sameAs 分子クラウディング.
- Macromolecular_crowding sameAs m.04ldd86.
- Macromolecular_crowding sameAs Q11396092.
- Macromolecular_crowding sameAs Q11396092.
- Macromolecular_crowding sameAs Macromolecular_crowding.
- Macromolecular_crowding wasDerivedFrom Macromolecular_crowding?oldid=592335105.
- Macromolecular_crowding depiction Crowded_cytosol.png.
- Macromolecular_crowding isPrimaryTopicOf Macromolecular_crowding.
