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- Metaphit abstract "Metaphit (1-[1-(3-Isothiocyanato)phenyl]cyclohexylpiperidine) is a research chemical that acts as an acylator of NMDARAn, sigma & DAT binding sites in the CNS. It is the m-isothiocyanate derivative of phencyclidine & binds irreversibly (forming a covalent bond) to the PCP binding site on the NMDA receptor complex. However, later studies suggest the functionality of metaphit is mediated by sites not involved in PCP-induced passive avoidance deficit, and not related to the NMDA receptor complex. Metaphit was also shown to prevent d-amphetamine induced hyperactivity, while significantly depleting dopamine content in the nucleus accumbens. Metaphit was the first acylating ligand used to study the cocaine receptor.".
- Metaphit iupacName "1-[1-(3-isothiocyanatophenyl)cyclohexyl]piperidine".
- Metaphit thumbnail Metaphit.svg?width=300.
- Metaphit wikiPageID "33741479".
- Metaphit wikiPageRevisionID "546257779".
- Metaphit hasPhotoCollection Metaphit.
- Metaphit imagefile "Metaphit.svg".
- Metaphit iupacname "1".
- Metaphit verifiedrevid "461743085".
- Metaphit subject Category:Dissociative_drugs.
- Metaphit subject Category:NMDA_receptor_antagonists.
- Metaphit subject Category:Piperidines.
- Metaphit subject Category:Sigma_agonists.
- Metaphit type Adversary109773245.
- Metaphit type CausalAgent100007347.
- Metaphit type LivingThing100004258.
- Metaphit type NMDAReceptorAntagonists.
- Metaphit type Object100002684.
- Metaphit type Organism100004475.
- Metaphit type Person100007846.
- Metaphit type PhysicalEntity100001930.
- Metaphit type Whole100003553.
- Metaphit type YagoLegalActor.
- Metaphit type YagoLegalActorGeo.
- Metaphit type ChemicalCompound.
- Metaphit type ChemicalSubstance.
- Metaphit type ChemicalObject.
- Metaphit type Thing.
- Metaphit comment "Metaphit (1-[1-(3-Isothiocyanato)phenyl]cyclohexylpiperidine) is a research chemical that acts as an acylator of NMDARAn, sigma & DAT binding sites in the CNS. It is the m-isothiocyanate derivative of phencyclidine & binds irreversibly (forming a covalent bond) to the PCP binding site on the NMDA receptor complex. However, later studies suggest the functionality of metaphit is mediated by sites not involved in PCP-induced passive avoidance deficit, and not related to the NMDA receptor complex.".
- Metaphit label "Metaphit".
- Metaphit sameAs m.0hhrg0s.
- Metaphit sameAs Q6553528.
- Metaphit sameAs Q6553528.
- Metaphit sameAs Metaphit.
- Metaphit wasDerivedFrom Metaphit?oldid=546257779.
- Metaphit depiction Metaphit.svg.
- Metaphit isPrimaryTopicOf Metaphit.
