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- Metapramine abstract "Metapramine (trade names Prodastene, Timaxel) is a tricyclic antidepressant (TCA) developed by Rhone Poulenc that was introduced for the treatment of depression in France in 1984. In addition to its efficacy against affective disorders, it also has analgesic properties, and may be useful in the treatment of pain.Metapramine has desipramine-like effects, acting as a norepinephrine reuptake inhibitor without affecting the reuptake of serotonin or dopamine. It has also been shown to act as a low-affinity NMDA receptor antagonist. Metapramine's direct effects on serotonin, histamine, and muscarinic acetylcholine receptors have not been assayed, but uniquely among most TCAs, it has anecdotally been reported to lack anticholinergic effects.".
- Metapramine atcPrefix "none".
- Metapramine casNumber "21730-16-5".
- Metapramine fdaUniiCode "303954M7YF".
- Metapramine iupacName "(±)-10,11-dihydro-N,5-dimethyl-5H-dibenz[b,f]azepin-10-amine".
- Metapramine pubchem "65700".
- Metapramine thumbnail Metapramine_skeletal.svg?width=300.
- Metapramine wikiPageID "25765838".
- Metapramine wikiPageRevisionID "592478823".
- Metapramine atcPrefix "none".
- Metapramine c "16".
- Metapramine casNumber "21730".
- Metapramine chemspiderid "59127".
- Metapramine drugName "Metapramine".
- Metapramine eliminationHalfLife "-28800.0".
- Metapramine h "18".
- Metapramine hasPhotoCollection Metapramine.
- Metapramine imagename "1".
- Metapramine iupacName "-1011".
- Metapramine legalStatus "Rx-only".
- Metapramine molecularWeight "238.33".
- Metapramine n "2".
- Metapramine pubchem "65700".
- Metapramine routesOfAdministration "Oral".
- Metapramine smiles "CNC1CC2=CNC3=CC=CC=C31".
- Metapramine unii "303954".
- Metapramine width "200".
- Metapramine subject Category:Dibenzazepines.
- Metapramine subject Category:Tricyclic_antidepressants.
- Metapramine type Agent114778436.
- Metapramine type Antidepressant102718811.
- Metapramine type CausalAgent100007347.
- Metapramine type Drug103247620.
- Metapramine type Matter100020827.
- Metapramine type Medicine103740161.
- Metapramine type PhysicalEntity100001930.
- Metapramine type Substance100020090.
- Metapramine type Tricyclic104482543.
- Metapramine type TricyclicAntidepressants.
- Metapramine type Drug.
- Metapramine type DrugProduct.
- Metapramine type FunctionalSubstance.
- Metapramine comment "Metapramine (trade names Prodastene, Timaxel) is a tricyclic antidepressant (TCA) developed by Rhone Poulenc that was introduced for the treatment of depression in France in 1984. In addition to its efficacy against affective disorders, it also has analgesic properties, and may be useful in the treatment of pain.Metapramine has desipramine-like effects, acting as a norepinephrine reuptake inhibitor without affecting the reuptake of serotonin or dopamine.".
- Metapramine label "Metapramine".
- Metapramine sameAs m.09v8f19.
- Metapramine sameAs Q15409392.
- Metapramine sameAs Q15409392.
- Metapramine sameAs Metapramine.
- Metapramine wasDerivedFrom Metapramine?oldid=592478823.
- Metapramine depiction Metapramine_skeletal.svg.
- Metapramine isPrimaryTopicOf Metapramine.
- Metapramine name "Metapramine".
