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- Metastasis abstract "Metastasis, or metastatic disease, is the spread of a cancer from one organ or part to another non-adjacent organ or part. The new occurrences of disease thus generated are referred to as metastases (sometimes abbreviated "mets"). It was previously thought that only malignant tumor cells and infections have the capacity to metastasize (also spelled metastasise); however, this is being reconsidered due to new research. In origin metastasis is a Greek word meaning "displacement", from μετά, meta, "next", and στάσις, stasis, "placement". The plural is metastases /mə ˈtæs tə siːz/.Cancer occurs after a single cell in a tissue is progressively genetically damaged to produce cells with uncontrolled proliferation. This uncontrolled proliferation, mitosis, produces a primary heterogeneic tumour. The cells which constitute the tumor eventually undergo metaplasia, followed by dysplasia then anaplasia, resulting in a malignant phenotype. This malignant phenotype allows for intravasation into the circulation, followed by extravasation to a second site for tumorigenesis.Some cancer cells acquire the ability to penetrate the walls of lymphatic and/or blood vessels, after which they are able to circulate through the bloodstream (circulating tumor cells) to other sites and tissues in the body. This process is known (respectively) as lymphatic or hematogenous spread.After the tumor cells come to rest at another site, they re-penetrate the vessel or walls and continue to multiply, eventually forming another clinically detectable tumor. This new tumor is known as a metastatic (or secondary) tumor. Metastasis is one of three hallmarks of malignancy (contrast benign tumors). Most neoplasms can metastasize, although in varying degrees (e.g., basal cell carcinoma rarely metastasize).When tumor cells metastasize, the new tumor is called a secondary or metastatic tumor, and its cells are similar to those in the original tumor. This means, for example, that, if breast cancer metastasizes to the lungs, the secondary tumor is made up of abnormal breast cells, not of abnormal lung cells. The tumor in the lung is then called metastatic breast cancer, not lung cancer.".
- Metastasis diseasesdb "28954".
- Metastasis medlineplus "002260".
- Metastasis thumbnail Metastasis_illustration.jpg?width=300.
- Metastasis wikiPageExternalLink metastatic.
- Metastasis wikiPageExternalLink mainpageS2029P23sublevel45.html.
- Metastasis wikiPageExternalLink www.kidcancer.org.
- Metastasis wikiPageExternalLink www.mbcnetwork.org.
- Metastasis wikiPageExternalLink www.metacancer.org.
- Metastasis wikiPageExternalLink bv.fcgi?rid=cmed.chapter.2030.
- Metastasis wikiPageID "152509".
- Metastasis wikiPageRevisionID "606023026".
- Metastasis caption "Illustration showing hematogeneous metastasis".
- Metastasis diseasesdb "28954".
- Metastasis hasPhotoCollection Metastasis.
- Metastasis medlineplus "2260".
- Metastasis name "Metastasis".
- Metastasis wordnet_type synset-disease-noun-1.
- Metastasis subject Category:Oncology.
- Metastasis type Disease.
- Metastasis type AilmentCondition.
- Metastasis type Situation.
- Metastasis comment "Metastasis, or metastatic disease, is the spread of a cancer from one organ or part to another non-adjacent organ or part. The new occurrences of disease thus generated are referred to as metastases (sometimes abbreviated "mets"). It was previously thought that only malignant tumor cells and infections have the capacity to metastasize (also spelled metastasise); however, this is being reconsidered due to new research.".
- Metastasis label "Metastase".
- Metastasis label "Metastasi".
- Metastasis label "Metastasis".
- Metastasis label "Metástase".
- Metastasis label "Metástasis".
- Metastasis label "Métastase (médecine)".
- Metastasis label "Przerzut nowotworowy".
- Metastasis label "Uitzaaiing".
- Metastasis label "Метастаз".
- Metastasis label "نقيلة".
- Metastasis label "転移 (医学)".
- Metastasis label "遠端轉移".
- Metastasis sameAs Metastáza.
- Metastasis sameAs Metastase.
- Metastasis sameAs Μετάσταση.
- Metastasis sameAs Metástasis.
- Metastasis sameAs Metastasi.
- Metastasis sameAs Métastase_(médecine).
- Metastasis sameAs Metastasis.
- Metastasis sameAs Metastasi.
- Metastasis sameAs 転移_(医学).
- Metastasis sameAs 전이_(의학).
- Metastasis sameAs Uitzaaiing.
- Metastasis sameAs Przerzut_nowotworowy.
- Metastasis sameAs Metástase.
- Metastasis sameAs m.013wmg.
- Metastasis sameAs Q181876.
- Metastasis sameAs Q181876.
- Metastasis wasDerivedFrom Metastasis?oldid=606023026.
- Metastasis depiction Metastasis_illustration.jpg.
- Metastasis isPrimaryTopicOf Metastasis.
- Metastasis name "Metastasis".
