Data Portal @ linkeddatafragments.org

Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Methadone> ?p ?o. }

• Methadone abstract "Methadone (also known as Symoron, Dolophine, Amidone, Methadose, Physeptone, Heptadon and many other names) is a synthetic opioid. It is used medically as an analgesic and a maintenance anti-addictive and reductive preparation for use by patients with opioid dependency. It was developed in Germany in 1937, mainly because Germany required a reliable internal source of opiates. Because it is an acyclic analog of morphine or heroin, methadone acts on the same opioid receptors as these drugs, and thus has many of the same effects. Methadone is also used in managing severe chronic pain, owing to its long duration of action, extremely powerful effects, and very low cost. Methadone was introduced into the United States in 1947 by Eli Lilly and Company. Abuse of methadone results in about 5,000 overdose deaths per year in the United States.Methadone is mainly used in the treatment of opioid dependence. It has cross-tolerance (tolerance to similar drugs) with other opioids including heroin and morphine, and offers very similar effects, but a longer duration of effect. Oral doses of methadone can stabilise patients by mitigating opioid withdrawal syndrome or making it more tolerable. Higher doses of methadone can block the euphoric effects of heroin, morphine, and similar drugs. As a result, properly dosed methadone patients can reduce or stop altogether their use of these substances.Methadone is approved for different indications in different countries. Common is approval as an analgesic and approval for the treatment of opioid dependence. It is not intended to reduce the use of non-opioid drugs such as methamphetamine, or alcohol.A number of pharmaceutical companies produce and distribute methadone. The racemic hydrochloride is the only form available in most countries, such as the Netherlands, Belgium, France and in the United States, as of March 2008. The dextrorotary enantiomer of methadone, dextromethadone, is an NMDA antagonist rather than an opiate agonist. Therefore, methadone medications used for opiate addiction sometimes only contain levomethadone, the levorotary enantiomer.[citation needed] Levomethadone is available under the trade names Polamidone and Heptadon, among others. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.".
• Methadone atcPrefix "N02".
• Methadone atcSuffix "AC52".
• Methadone bioavailability "41.0".
• Methadone casNumber "76-99-3".
• Methadone chEBI "6807".
• Methadone drugbank "DB00333".
• Methadone fdaUniiCode "UC6VBE7V1Z".
• Methadone iupacName "(RS)-6-(Dimethylamino)-4,4-diphenylheptan-3-one".
• Methadone pubchem "4095".
• Methadone thumbnail Methadone.svg?width=300.
• Methadone wikiPageExternalLink treatment.
• Methadone wikiPageExternalLink dpdirect.jsp?name=Methadone.
• Methadone wikiPageExternalLink 18_Methadone%20Hydrochloride%20Tab_REV011309.pdf.
• Methadone wikiPageExternalLink www.MethadoneSupport.org.
• Methadone wikiPageExternalLink Tapering%20off%20of%20Methadone%20Maintenance%205-24-02.pdf.
• Methadone wikiPageExternalLink MethadoneFin.pdf.
• Methadone wikiPageExternalLink methadone-bp-mp-eng.pdf.
• Methadone wikiPageExternalLink www.methadone.org.
• Methadone wikiPageExternalLink www.methadone.us.
• Methadone wikiPageExternalLink methadone_clinic_directory.
• Methadone wikiPageExternalLink index.html.
• Methadone wikiPageID "20962".
• Methadone wikiPageRevisionID "606440813".
• Methadone atcPrefix "N02".
• Methadone atcSuffix "AC52".
• Methadone bioavailability "41".
• Methadone c "21".
• Methadone casNumber "76".
• Methadone chebi "6807".
• Methadone chembl "651".
• Methadone chemspiderid "3953".
• Methadone drugName "Methadone".
• Methadone drugbank "DB00333".
• Methadone eliminationHalfLife "-234000.0".
• Methadone excretion "Urine, faeces".
• Methadone h "27".
• Methadone hasPhotoCollection Methadone.
• Methadone image "Methadone3DanJ.gif".
• Methadone imagename "1".
• Methadone inchi "1".
• Methadone iupacName "-6".
• Methadone iupharLigand "1605".
• Methadone kegg "D08195".
• Methadone legalAu "Schedule 8".
• Methadone legalUk "Class A".
• Methadone legalUs "Schedule II".
• Methadone medlineplus "a682134".
• Methadone metabolism "Hepatic".
• Methadone molecularWeight "309.445".
• Methadone n "1".
• Methadone o "1".
• Methadone pregnancyAu "C".
• Methadone pregnancyUs "C".
• Methadone proteinBinding "85".
• Methadone pubchem "4095".
• Methadone routesOfAdministration "Oral, intravenous, insufflation, sublingual, rectal".
• Methadone smiles "CCC=O".
• Methadone stdinchi "1".
• Methadone stdinchikey "USSIQXCVUWKGNF-UHFFFAOYSA-N".
• Methadone tradename "Dolophine".
• Methadone unii "UC6VBE7V1Z".
• Methadone verifiedfields "changed".
• Methadone verifiedrevid "420419989".
• Methadone watchedfields "changed".
• Methadone width "180".
• Methadone width "280".
• Methadone subject Category:Amines.
• Methadone subject Category:Drug_rehabilitation.
• Methadone subject Category:Eli_Lilly_and_Company.
• Methadone subject Category:Euphoriants.
• Methadone subject Category:Inventions_of_the_Third_Reich.
• Methadone subject Category:Ketones.
• Methadone subject Category:Mu-opioid_agonists.
• Methadone subject Category:Synthetic_opioids.
• Methadone type Drug.
• Methadone type DrugProduct.
• Methadone type FunctionalSubstance.
• Methadone comment "Methadone (also known as Symoron, Dolophine, Amidone, Methadose, Physeptone, Heptadon and many other names) is a synthetic opioid. It is used medically as an analgesic and a maintenance anti-addictive and reductive preparation for use by patients with opioid dependency. It was developed in Germany in 1937, mainly because Germany required a reliable internal source of opiates.".
• Methadone label "Metadon".
• Methadone label "Metadona".
• Methadone label "Metadona".
• Methadone label "Metadone".
• Methadone label "Methadon".
• Methadone label "Methadon".
• Methadone label "Methadone".
• Methadone label "Méthadone".
• Methadone label "Метадон".
• Methadone label "メタドン".
• Methadone label "美沙酮".
• Methadone sameAs Metadon.
• Methadone sameAs Methadon.
• Methadone sameAs Μεθαδόνη.
• Methadone sameAs Metadona.
• Methadone sameAs Metadona.
• Methadone sameAs Méthadone.
• Methadone sameAs Metadon.
• Methadone sameAs Metadone.
• Methadone sameAs メタドン.
• Methadone sameAs 메타돈.

• next