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- Midostaurin abstract "Midostaurin (PKC412) is a multi-target protein kinase inhibitor being investigated for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). It is a semi-synthetic derivative of staurosporine, an alkaloid from the bacterium Streptomyces staurosporeus, and is active in patients with mutations of CD135 (FMS-like tyrosine kinase 3 receptor).After successful Phase II clinical trials, a Phase III trial for AML has started in 2008. It is testing midostaurin in combination with daunorubicin and cytarabine. In another trial, the substance has proven ineffective in metastatic melanoma.".
- Midostaurin atcPrefix "None".
- Midostaurin casNumber "120685-11-2".
- Midostaurin fdaUniiCode "ID912S5VON".
- Midostaurin iupacName "(9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiamzonine-1-one".
- Midostaurin pubchem "9829523".
- Midostaurin thumbnail Midostaurin_skeletal.svg?width=300.
- Midostaurin wikiPageID "30532906".
- Midostaurin wikiPageRevisionID "546077280".
- Midostaurin atcPrefix "None".
- Midostaurin c "35".
- Midostaurin casNumber "120685".
- Midostaurin chembl "608533".
- Midostaurin chemspiderid "8005258".
- Midostaurin h "30".
- Midostaurin hasPhotoCollection Midostaurin.
- Midostaurin inchi "1".
- Midostaurin inchikey "BMGQWWVMWDBQGC-IIFHNQTCBG".
- Midostaurin iupacName "-2310111213".
- Midostaurin legalStatus "Investigational".
- Midostaurin molecularWeight "570.637".
- Midostaurin n "4".
- Midostaurin o "4".
- Midostaurin pubchem "9829523".
- Midostaurin routesOfAdministration "Oral".
- Midostaurin smiles "CC12C".
- Midostaurin stdinchi "1".
- Midostaurin stdinchikey "BMGQWWVMWDBQGC-IIFHNQTCSA-N".
- Midostaurin synonyms "4".
- Midostaurin unii "ID912S5VON".
- Midostaurin width "150".
- Midostaurin subject Category:Alkaloids.
- Midostaurin subject Category:Indolocarbazoles.
- Midostaurin subject Category:Lactams.
- Midostaurin subject Category:Protein_kinase_inhibitors.
- Midostaurin type Abstraction100002137.
- Midostaurin type Alkaloid114712692.
- Midostaurin type Alkaloids.
- Midostaurin type Chemical114806838.
- Midostaurin type Compound114818238.
- Midostaurin type Material114580897.
- Midostaurin type Matter100020827.
- Midostaurin type OrganicCompound114727670.
- Midostaurin type Part113809207.
- Midostaurin type PhysicalEntity100001930.
- Midostaurin type Relation100031921.
- Midostaurin type Substance100019613.
- Midostaurin type Drug.
- Midostaurin type FunctionalSubstance.
- Midostaurin comment "Midostaurin (PKC412) is a multi-target protein kinase inhibitor being investigated for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). It is a semi-synthetic derivative of staurosporine, an alkaloid from the bacterium Streptomyces staurosporeus, and is active in patients with mutations of CD135 (FMS-like tyrosine kinase 3 receptor).After successful Phase II clinical trials, a Phase III trial for AML has started in 2008.".
- Midostaurin label "Midostaurin".
- Midostaurin label "ミドスタウリン".
- Midostaurin sameAs ミドスタウリン.
- Midostaurin sameAs m.0g9vkns.
- Midostaurin sameAs Q6842945.
- Midostaurin sameAs Q6842945.
- Midostaurin sameAs Midostaurin.
- Midostaurin wasDerivedFrom Midostaurin?oldid=546077280.
- Midostaurin depiction Midostaurin_skeletal.svg.
- Midostaurin isPrimaryTopicOf Midostaurin.
