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- 215_microRNA_precursor abstract "The miR-192 microRNA precursor (homologous to miR-215), is a short non-coding RNAgene involved in gene regulation.miR-192 and miR-215 have now been predicted or experimentally confirmed in mouse and human.microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In this case the mature sequence comes from the 5' arm of the precursor. The mature products are thought to haveregulatory roles through complementarity to mRNA.mir-192 and mir-215 are thought to be positive regulators of p53, a human tumour suppressor. They are also overexpressed in gastric cancer, and could potentially be used as biomarkers or therapeutic targets. It has also been suggested that mir-192 could be used as a biomarker for drug-induced liver damage.".
- 215_microRNA_precursor thumbnail RF00130.jpg?width=300.
- 215_microRNA_precursor wikiPageExternalLink mirna_summary.pl?fam=MIPF0000063.
- 215_microRNA_precursor wikiPageID "11420924".
- 215_microRNA_precursor wikiPageRevisionID "589641808".
- 215_microRNA_precursor caption "Predicted secondary structure and sequence conservation of mir-192".
- 215_microRNA_precursor hasPhotoCollection 215_microRNA_precursor.
- 215_microRNA_precursor id "RF00130".
- 215_microRNA_precursor mirbase "MI0000234".
- 215_microRNA_precursor mirbaseFamily "MIPF0000063".
- 215_microRNA_precursor name "mir-192/215 microRNA precursor".
- 215_microRNA_precursor rfam "RF00130".
- 215_microRNA_precursor rnaType Gene.
- 215_microRNA_precursor rnaType MicroRNA.
- 215_microRNA_precursor symbol "mir-192".
- 215_microRNA_precursor taxDomain Eukaryote.
- 215_microRNA_precursor subject Category:MicroRNA.
- 215_microRNA_precursor comment "The miR-192 microRNA precursor (homologous to miR-215), is a short non-coding RNAgene involved in gene regulation.miR-192 and miR-215 have now been predicted or experimentally confirmed in mouse and human.microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In this case the mature sequence comes from the 5' arm of the precursor.".
- 215_microRNA_precursor label "Mir-192/215 microRNA precursor".
- 215_microRNA_precursor sameAs m.02rbyb1.
- 215_microRNA_precursor sameAs Q6871690.
- 215_microRNA_precursor sameAs Q6871690.
- 215_microRNA_precursor wasDerivedFrom 215_microRNA_precursor?oldid=589641808.
- 215_microRNA_precursor depiction RF00130.jpg.
- 215_microRNA_precursor isPrimaryTopicOf 215_microRNA_precursor.
