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- Mir-30_microRNA_precursor abstract "miR-30 microRNA precursor is a small non-coding RNA that regulates gene expression. Animal microRNAs are transcribed as pri-miRNA (primary miRNA) of varying length which in turns are processed in the nucleus by Drosha into ~70 nucleotide stem-loop precursor called pre-miRNA (preliminary miRNA) and subsequently processed by the Dicer enzyme to give a mature ~22 nucleotide product. In this case the mature sequence comes from both the 3' (miR-30) and 5' (mir-97-6) arms of the precursor. The products are thought to have regulatory roles through complementarity to mRNA.A screen of 17 miRNAs that have been predicted to regulate a number of breast cancer associated genes found variations in the microRNAsmiR-17 and miR-30c-1, these patients were noncarriers of BRCA1 or BRCA2 mutations, lending the possibility that familial breast cancer may be caused by variation in these miRNAs.Members of the miR-30 family have been found to be highly expressed in heart cells.".
- Mir-30_microRNA_precursor thumbnail RF00131.jpg?width=300.
- Mir-30_microRNA_precursor wikiPageID "11421279".
- Mir-30_microRNA_precursor wikiPageRevisionID "592515176".
- Mir-30_microRNA_precursor caption "Predicted secondary structure and sequence conservation of mir-30".
- Mir-30_microRNA_precursor hasPhotoCollection Mir-30_microRNA_precursor.
- Mir-30_microRNA_precursor id "RF00131".
- Mir-30_microRNA_precursor mirbase "MI0000088".
- Mir-30_microRNA_precursor mirbaseFamily "MIPF0000005".
- Mir-30_microRNA_precursor name "mir-30 microRNA precursor".
- Mir-30_microRNA_precursor rfam "RF00131".
- Mir-30_microRNA_precursor rnaType Gene.
- Mir-30_microRNA_precursor rnaType MicroRNA.
- Mir-30_microRNA_precursor symbol "mir-30".
- Mir-30_microRNA_precursor taxDomain Eukaryote.
- Mir-30_microRNA_precursor subject Category:MicroRNA.
- Mir-30_microRNA_precursor comment "miR-30 microRNA precursor is a small non-coding RNA that regulates gene expression. Animal microRNAs are transcribed as pri-miRNA (primary miRNA) of varying length which in turns are processed in the nucleus by Drosha into ~70 nucleotide stem-loop precursor called pre-miRNA (preliminary miRNA) and subsequently processed by the Dicer enzyme to give a mature ~22 nucleotide product. In this case the mature sequence comes from both the 3' (miR-30) and 5' (mir-97-6) arms of the precursor.".
- Mir-30_microRNA_precursor label "Mir-30 microRNA precursor".
- Mir-30_microRNA_precursor sameAs m.02rbzd2.
- Mir-30_microRNA_precursor sameAs Q6871745.
- Mir-30_microRNA_precursor sameAs Q6871745.
- Mir-30_microRNA_precursor wasDerivedFrom Mir-30_microRNA_precursor?oldid=592515176.
- Mir-30_microRNA_precursor depiction RF00131.jpg.
- Mir-30_microRNA_precursor isPrimaryTopicOf Mir-30_microRNA_precursor.
