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- Missing_heritability_problem abstract "The "missing heritability" problem can be defined as the fact that individual genes cannot account for much of the heritability of diseases, behaviors, and other phenotypes. This is a problem that has significant implications for medicine, since a person's susceptibility to disease may depend more on "the combined effect of all the genes in the background than on the disease genes in the foreground".A model has been introduced that takes into account epigenetic inheritance on the risk and recurrence risk of a complex disease.The limiting pathway (LP) model has been introduced in which a trait depends on the value of k inputs that can have rate limitations due to stoichiometric ratios, reactants required in a biochemical pathway, or proteins required for transcription of a gene. Each of these k inputs is a strictly additive trait that depends on a set of common or rare variants. When k = 1, the LP model is simply a standard additive trait.".
- Missing_heritability_problem wikiPageID "34853851".
- Missing_heritability_problem wikiPageRevisionID "554889479".
- Missing_heritability_problem hasPhotoCollection Missing_heritability_problem.
- Missing_heritability_problem subject Category:Epigenetics.
- Missing_heritability_problem subject Category:Genetics.
- Missing_heritability_problem comment "The "missing heritability" problem can be defined as the fact that individual genes cannot account for much of the heritability of diseases, behaviors, and other phenotypes.".
- Missing_heritability_problem label "Heredabilidad perdida".
- Missing_heritability_problem label "Missing heritability problem".
- Missing_heritability_problem sameAs Heredabilidad_perdida.
- Missing_heritability_problem sameAs m.0j43n2t.
- Missing_heritability_problem sameAs Q3083720.
- Missing_heritability_problem sameAs Q3083720.
- Missing_heritability_problem wasDerivedFrom Missing_heritability_problem?oldid=554889479.
- Missing_heritability_problem isPrimaryTopicOf Missing_heritability_problem.