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- Mizoribine abstract "Mizoribine (INN, trade name Bredinin) is an immunosuppressive drug. The compound was first observed in Tokyo, Japan, in 1971. It is a natural product, first isolated from the mould Eupenicillium brefeldianum. Mizoribine (MZB) is an imidazole nucleoside that has been used in renal transplantation, and in steroid-resistant nephrotic syndrome, IgA nephropathy, lupus, as well as for adults with rheumatoid arthritis, lupus nephritis and other rheumatic diseases. MZB exerts its activity through selective inhibition of inosine monophosphate synthetase and guanosine monophosphate synthetase, resulting in the complete inhibition of guanine nucleotide synthesis without incorporation into nucleotides. It arrests DNA synthesis in the S phase of cellular division. Thus, MZB has less toxicity than azathioprine, another immunosuppressant used for some of the same diseases.".
- Mizoribine atcPrefix "none".
- Mizoribine casNumber "50924-49-7".
- Mizoribine fdaUniiCode "4JR41A10VP".
- Mizoribine iupacName "5-hydroxy-1-β-(D)-ribofuranosyl-1H-imidazole-4-carboxamide".
- Mizoribine pubchem "104762".
- Mizoribine thumbnail Mizoribine.png?width=300.
- Mizoribine wikiPageID "18634413".
- Mizoribine wikiPageRevisionID "522345760".
- Mizoribine atcPrefix "none".
- Mizoribine c "9".
- Mizoribine casNumber "50924".
- Mizoribine h "13".
- Mizoribine hasPhotoCollection Mizoribine.
- Mizoribine iupacName "5".
- Mizoribine kegg "D01392".
- Mizoribine legalStatus "Rx-only".
- Mizoribine molecularWeight "259.21".
- Mizoribine n "3".
- Mizoribine o "6".
- Mizoribine pubchem "104762".
- Mizoribine routesOfAdministration "Oral".
- Mizoribine smiles "C1=NCCN".
- Mizoribine synonyms "(1-[-3,4-dihydroxy-5-oxolan-2-yl]-5-hydroxyimidazole-4-carboxamide)".
- Mizoribine unii "4".
- Mizoribine verifiedrevid "444901837".
- Mizoribine subject Category:Immunosuppressants.
- Mizoribine type Agent114778436.
- Mizoribine type CausalAgent100007347.
- Mizoribine type Drug103247620.
- Mizoribine type Immunosuppressant103562958.
- Mizoribine type Immunosuppressants.
- Mizoribine type Matter100020827.
- Mizoribine type Medicine103740161.
- Mizoribine type PhysicalEntity100001930.
- Mizoribine type Substance100020090.
- Mizoribine type Drug.
- Mizoribine type DrugProduct.
- Mizoribine type FunctionalSubstance.
- Mizoribine comment "Mizoribine (INN, trade name Bredinin) is an immunosuppressive drug. The compound was first observed in Tokyo, Japan, in 1971. It is a natural product, first isolated from the mould Eupenicillium brefeldianum. Mizoribine (MZB) is an imidazole nucleoside that has been used in renal transplantation, and in steroid-resistant nephrotic syndrome, IgA nephropathy, lupus, as well as for adults with rheumatoid arthritis, lupus nephritis and other rheumatic diseases.".
- Mizoribine label "Mizoribine".
- Mizoribine sameAs m.04gp88h.
- Mizoribine sameAs Q6884708.
- Mizoribine sameAs Q6884708.
- Mizoribine sameAs Mizoribine.
- Mizoribine wasDerivedFrom Mizoribine?oldid=522345760.
- Mizoribine depiction Mizoribine.png.
- Mizoribine isPrimaryTopicOf Mizoribine.
