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- Monoamine_reuptake_inhibitor abstract "A monoamine reuptake inhibitor (MRI) is a drug that acts as a reuptake inhibitor of one or more of the three major monoamine neurotransmitters serotonin, norepinephrine, and dopamine by blocking the action of one or more of the respective monoamine transporters (MATs), of which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT). This in turn results in an increase in the synaptic concentrations of one or more of these neurotransmitters and therefore an increase in monoaminergic neurotransmission.The majority of currently approved antidepressants act predominantly as MRIs, including the selective serotonin reuptake inhibitors (SSRIs) and most of the tricyclic antidepressants (TCAs). Many psychostimulants used either as anorectics or in the treatment of ADHD also behave as MRIs. Additionally, psychostimulants acting as MRIs that affect dopamine such as cocaine and methylphenidate are often abused as recreational drugs. As a result, many of them have become controlled substances, which in turn has resulted in the clandestine synthesis of a vast array of designer drugs for the purpose of bypassing drug laws, a prime example of such is the mixed monoamine reuptake inhibitor and releasing agent mephedrone.".
- Monoamine_reuptake_inhibitor thumbnail Serotonin_(5-HT).svg?width=300.
- Monoamine_reuptake_inhibitor wikiPageID "35778489".
- Monoamine_reuptake_inhibitor wikiPageRevisionID "592581121".
- Monoamine_reuptake_inhibitor hasPhotoCollection Monoamine_reuptake_inhibitor.
- Monoamine_reuptake_inhibitor subject Category:Drugs_acting_on_the_nervous_system.
- Monoamine_reuptake_inhibitor subject Category:Monoamine_reuptake_inhibitors.
- Monoamine_reuptake_inhibitor comment "A monoamine reuptake inhibitor (MRI) is a drug that acts as a reuptake inhibitor of one or more of the three major monoamine neurotransmitters serotonin, norepinephrine, and dopamine by blocking the action of one or more of the respective monoamine transporters (MATs), of which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).".
- Monoamine_reuptake_inhibitor label "Monoamine reuptake inhibitor".
- Monoamine_reuptake_inhibitor sameAs m.0jt3y78.
- Monoamine_reuptake_inhibitor sameAs Q16155077.
- Monoamine_reuptake_inhibitor sameAs Q16155077.
- Monoamine_reuptake_inhibitor wasDerivedFrom Monoamine_reuptake_inhibitor?oldid=592581121.
- Monoamine_reuptake_inhibitor depiction Serotonin_(5-HT).svg.
- Monoamine_reuptake_inhibitor isPrimaryTopicOf Monoamine_reuptake_inhibitor.