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- Myelin_basic_protein abstract "Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction. MBP maintain the correct structure of myelin, interacting with the lipids in the myelin membrane.MBP was initially sequenced in 1971 after isolation from myelin membranes. Since that time, knockout mice deficient in MBP that showed decreased amounts of CNS myelination and a progressive disorder characterized by tremors, seizures, and early death have been developed. The human gene for MBP is on chromosome 18; the protein localizes to the CNS and to various cells of the hematopoietic system.The pool of MBP in the central nervous system is very diverse, with several splice variants being expressed and a large number of post-translational modifications on the protein, which include phosphorylation, methylation, deamidation, and citrullination. These forms differ by the presence or the absence of short (10 to 20 residues) peptides in various internal locations in the sequence. In general, the major form of MBP is a protein of about 18.5 Kd (170 residues).In melanocytic cell types, MBP gene expression may be regulated by MITF.".
- Myelin_basic_protein entrezgene "4155".
- Myelin_basic_protein symbol "Myelin_MBP".
- Myelin_basic_protein wikiPageID "2862913".
- Myelin_basic_protein wikiPageRevisionID "606349484".
- Myelin_basic_protein hasPhotoCollection Myelin_basic_protein.
- Myelin_basic_protein interpro "IPR000548".
- Myelin_basic_protein name "Myelin_MBP".
- Myelin_basic_protein opmFamily "464".
- Myelin_basic_protein opmProtein "2".
- Myelin_basic_protein pfam "PF01669".
- Myelin_basic_protein prosite "PDOC00492".
- Myelin_basic_protein requireManualInspection "no".
- Myelin_basic_protein scop "1".
- Myelin_basic_protein symbol "Myelin_MBP".
- Myelin_basic_protein updateCitations "yes".
- Myelin_basic_protein updatePage "yes".
- Myelin_basic_protein updateProteinBox "yes".
- Myelin_basic_protein updateSummary "no".
- Myelin_basic_protein subject Category:Human_proteins.
- Myelin_basic_protein subject Category:Peripheral_membrane_proteins.
- Myelin_basic_protein subject Category:Protein_families.
- Myelin_basic_protein type Abstraction100002137.
- Myelin_basic_protein type Chemical114806838.
- Myelin_basic_protein type Compound114818238.
- Myelin_basic_protein type HumanProteins.
- Myelin_basic_protein type Macromolecule114944888.
- Myelin_basic_protein type Material114580897.
- Myelin_basic_protein type Matter100020827.
- Myelin_basic_protein type Molecule114682133.
- Myelin_basic_protein type OrganicCompound114727670.
- Myelin_basic_protein type Part113809207.
- Myelin_basic_protein type PeripheralMembraneProteins.
- Myelin_basic_protein type PhysicalEntity100001930.
- Myelin_basic_protein type Protein114728724.
- Myelin_basic_protein type Relation100031921.
- Myelin_basic_protein type Substance100019613.
- Myelin_basic_protein type Thing100002452.
- Myelin_basic_protein type Unit109465459.
- Myelin_basic_protein type Biomolecule.
- Myelin_basic_protein type Protein.
- Myelin_basic_protein type BiologicalObject.
- Myelin_basic_protein comment "Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction. MBP maintain the correct structure of myelin, interacting with the lipids in the myelin membrane.MBP was initially sequenced in 1971 after isolation from myelin membranes.".
- Myelin_basic_protein label "Basisches Myelinprotein".
- Myelin_basic_protein label "Myelin basic protein".
- Myelin_basic_protein label "Основной белок миелина".
- Myelin_basic_protein label "髓鞘鹼性蛋白".
- Myelin_basic_protein sameAs Basisches_Myelinprotein.
- Myelin_basic_protein sameAs m.087l1n.
- Myelin_basic_protein sameAs Q410974.
- Myelin_basic_protein sameAs Q410974.
- Myelin_basic_protein sameAs 3632.
- Myelin_basic_protein sameAs Myelin_basic_protein.
- Myelin_basic_protein wasDerivedFrom Myelin_basic_protein?oldid=606349484.
- Myelin_basic_protein isPrimaryTopicOf Myelin_basic_protein.