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- Myogenic_determination_factor_5 abstract "In molecular biology, the myogenic determination factor 5 proteins are a family of proteins found in eukaryotes. This family includes the Myf5 protein, which is responsible for directing cells to the skeletal myocyte lineage during development. Myf5 is likely to act in a similar way to the other MRF4 proteins such as MyoD which perform the same function. These are histone acetyltransferases and histone deacetylases which activate and repress genes involved in the myocyte lineage. Myogenic determination factor 5 proteins contain three conserved protein domains. A C-terminal Myf5 domain, a central basic helix-loop-helix (bHLH) domain and an N-terminal basic domain. The bHLH region mediates specific DNA binding. With 12 residues of the basic domain involved in DNA binding. The basic domain forms an extended alpha helix in the structure.".
- Myogenic_determination_factor_5 symbol "Basic".
- Myogenic_determination_factor_5 symbol "Myf5".
- Myogenic_determination_factor_5 thumbnail PDB_1mdy_EBI.jpg?width=300.
- Myogenic_determination_factor_5 wikiPageID "32159587".
- Myogenic_determination_factor_5 wikiPageRevisionID "592607501".
- Myogenic_determination_factor_5 caption "crystal structure of myod bhlh domain bound to dna: perspectives on dna recognition and implications for transcriptional activation".
- Myogenic_determination_factor_5 hasPhotoCollection Myogenic_determination_factor_5.
- Myogenic_determination_factor_5 interpro "IPR002546".
- Myogenic_determination_factor_5 interpro "IPR022032".
- Myogenic_determination_factor_5 name "Basic domain".
- Myogenic_determination_factor_5 name "Myf5 domain".
- Myogenic_determination_factor_5 pfam "PF01586".
- Myogenic_determination_factor_5 pfam "PF12232".
- Myogenic_determination_factor_5 prosite "PDOC00038".
- Myogenic_determination_factor_5 scop "1".
- Myogenic_determination_factor_5 symbol "Basic".
- Myogenic_determination_factor_5 symbol "Myf5".
- Myogenic_determination_factor_5 subject Category:Protein_families.
- Myogenic_determination_factor_5 type Biomolecule.
- Myogenic_determination_factor_5 type Protein.
- Myogenic_determination_factor_5 type BiologicalObject.
- Myogenic_determination_factor_5 comment "In molecular biology, the myogenic determination factor 5 proteins are a family of proteins found in eukaryotes. This family includes the Myf5 protein, which is responsible for directing cells to the skeletal myocyte lineage during development. Myf5 is likely to act in a similar way to the other MRF4 proteins such as MyoD which perform the same function. These are histone acetyltransferases and histone deacetylases which activate and repress genes involved in the myocyte lineage.".
- Myogenic_determination_factor_5 label "Myogenic determination factor 5".
- Myogenic_determination_factor_5 sameAs m.0gx166r.
- Myogenic_determination_factor_5 sameAs Q6947922.
- Myogenic_determination_factor_5 sameAs Q6947922.
- Myogenic_determination_factor_5 wasDerivedFrom Myogenic_determination_factor_5?oldid=592607501.
- Myogenic_determination_factor_5 depiction PDB_1mdy_EBI.jpg.
- Myogenic_determination_factor_5 isPrimaryTopicOf Myogenic_determination_factor_5.
