Matches in DBpedia 2014 for { <http://dbpedia.org/resource/NANS> ?p ?o. }
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- NANS abstract "Sialic acid synthase is an enzyme that in humans is encoded by the NANS gene.This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively. However, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.".
- NANS entrezgene "54187".
- NANS wikiPageID "15349262".
- NANS wikiPageRevisionID "592613193".
- NANS hasPhotoCollection NANS.
- NANS requireManualInspection "no".
- NANS summaryText "This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid , respectively. However, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.".
- NANS updateCitations "yes".
- NANS updatePage "yes".
- NANS updateProteinBox "yes".
- NANS updateSummary "yes".
- NANS subject Category:Human_proteins.
- NANS type Abstraction100002137.
- NANS type Chemical114806838.
- NANS type Compound114818238.
- NANS type HumanProteins.
- NANS type Macromolecule114944888.
- NANS type Material114580897.
- NANS type Matter100020827.
- NANS type Molecule114682133.
- NANS type OrganicCompound114727670.
- NANS type Part113809207.
- NANS type PhysicalEntity100001930.
- NANS type Protein114728724.
- NANS type Relation100031921.
- NANS type Substance100019613.
- NANS type Thing100002452.
- NANS type Unit109465459.
- NANS type Biomolecule.
- NANS type Protein.
- NANS type BiologicalObject.
- NANS comment "Sialic acid synthase is an enzyme that in humans is encoded by the NANS gene.This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively. However, it exhibits much higher activity toward the Neu5Ac phosphate product.".
- NANS label "NANS".
- NANS sameAs NANS.
- NANS sameAs m.03m5vrj.
- NANS sameAs Q6952315.
- NANS sameAs Q6952315.
- NANS sameAs NANS.
- NANS wasDerivedFrom NANS?oldid=592613193.
- NANS isPrimaryTopicOf NANS.