Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Natural_killer_cell> ?p ?o. }
Showing items 1 to 59 of
59
with 100 items per page.
- Natural_killer_cell abstract "Natural Killer Cells (or NK cells) are a type of cytotoxic lymphocyte critical to the innate immune system. The role NK cells play is analogous to that of cytotoxic T cells in the vertebrate adaptive immune response. NK cells provide rapid responses to virally infected cells and respond to tumor formation, acting at around 3 days after infection. Typically immune cells detect MHC presented on infected cell surfaces, triggering cytokine release, causing lysis or apoptosis. NK cells are unique, however, as they have the ability to recognize stressed cells in the absence of antibodies and MHC, allowing for a much faster immune reaction. They were named “natural killers” because of the initial notion that they do not require activation in order to kill cells that are missing “self” markers of major histocompatibility complex (MHC) class 1.NK cells (belonging to the group of Innate lymphoid cells) are defined as large granular lymphocytes (LGL) and constitute the third kind of cells differentiated from the common lymphoid progenitor generating B and T lymphocytes. NK cells are known to differentiate and mature in the bone marrow, lymph node, spleen, tonsils and thymus where they then enter into the circulation. NK cells differ from Natural Killer T cells (NKT) phenotypically, by origin and by respective effector functions; often NKT cell activity promotes NK cell activity by secreting IFNγ. In contrast to NKT cells, NK cells do not express T-cell antigen receptors (TCR) or Pan T marker CD3 or surface immunoglobulins (Ig) B cell receptors, but they usually express the surface markers CD16 (FcγRIII) and CD56 in humans, NK1.1 or NK1.2 in C57BL/6 mice. Up to 80% of human NK cells also express CD8.In addition to the knowledge that natural killer cells are effectors of innate immunity, recent research has uncovered information on both activating and inhibitory NK cell receptors which play important function roles including self tolerance and sustaining NK cell activity. NK cell also play a role in adaptive immune response, numerous experiments have worked to demonstrate their ability to readily adjust to the immediate environment and formulate antigen-specific immunological memory, fundamental for responding to secondary infections with the same antigen. The ability for NK cells to act in both the innate and adaptive immune response is becoming increasingly important in research utilizing NK cell activity and potential cancer therapies.".
- Natural_killer_cell thumbnail HLA-Cw4.png?width=300.
- Natural_killer_cell wikiPageExternalLink default.aspx?objid=58465.
- Natural_killer_cell wikiPageExternalLink dictionary?CdrID=44440.
- Natural_killer_cell wikiPageExternalLink cope.cgi?key=NK-cells.
- Natural_killer_cell wikiPageExternalLink fertility-treatment-options-reproductive-immunology.html.
- Natural_killer_cell wikiPageExternalLink 817-natural-body-guards-killer-cells-motivated.html.
- Natural_killer_cell wikiPageExternalLink www.nkcells.info.
- Natural_killer_cell wikiPageExternalLink watch?v=HNP1EAYLhOs.
- Natural_killer_cell wikiPageID "211955".
- Natural_killer_cell wikiPageRevisionID "605108455".
- Natural_killer_cell hasPhotoCollection Natural_killer_cell.
- Natural_killer_cell subject Category:Human_cells.
- Natural_killer_cell subject Category:Lymphocytes.
- Natural_killer_cell type Abstraction100002137.
- Natural_killer_cell type AmorphousShape113867492.
- Natural_killer_cell type Attribute100024264.
- Natural_killer_cell type Cell102991711.
- Natural_killer_cell type Compartment103080309.
- Natural_killer_cell type HumanCells.
- Natural_killer_cell type Location100027167.
- Natural_killer_cell type Object100002684.
- Natural_killer_cell type PhysicalEntity100001930.
- Natural_killer_cell type Shape100027807.
- Natural_killer_cell type Space113910384.
- Natural_killer_cell type YagoGeoEntity.
- Natural_killer_cell type YagoLegalActorGeo.
- Natural_killer_cell type YagoPermanentlyLocatedEntity.
- Natural_killer_cell comment "Natural Killer Cells (or NK cells) are a type of cytotoxic lymphocyte critical to the innate immune system. The role NK cells play is analogous to that of cytotoxic T cells in the vertebrate adaptive immune response. NK cells provide rapid responses to virally infected cells and respond to tumor formation, acting at around 3 days after infection. Typically immune cells detect MHC presented on infected cell surfaces, triggering cytokine release, causing lysis or apoptosis.".
- Natural_killer_cell label "Célula NK".
- Natural_killer_cell label "Célula exterminadora natural".
- Natural_killer_cell label "Komórki NK".
- Natural_killer_cell label "Linfocita NK".
- Natural_killer_cell label "Lymphocyte NK".
- Natural_killer_cell label "NK-Zelle".
- Natural_killer_cell label "NK-cel".
- Natural_killer_cell label "Natural killer cell".
- Natural_killer_cell label "Естественные киллеры".
- Natural_killer_cell label "خلية فاتكة طبيعية".
- Natural_killer_cell label "ナチュラルキラー細胞".
- Natural_killer_cell label "自然杀伤细胞".
- Natural_killer_cell sameAs NK_buňka.
- Natural_killer_cell sameAs NK-Zelle.
- Natural_killer_cell sameAs Célula_NK.
- Natural_killer_cell sameAs NK_zelula.
- Natural_killer_cell sameAs Lymphocyte_NK.
- Natural_killer_cell sameAs Linfocita_NK.
- Natural_killer_cell sameAs ナチュラルキラー細胞.
- Natural_killer_cell sameAs 자연_살해_세포.
- Natural_killer_cell sameAs NK-cel.
- Natural_killer_cell sameAs Komórki_NK.
- Natural_killer_cell sameAs Célula_exterminadora_natural.
- Natural_killer_cell sameAs m.01f1yy.
- Natural_killer_cell sameAs Q332181.
- Natural_killer_cell sameAs Q332181.
- Natural_killer_cell sameAs Natural_killer_cell.
- Natural_killer_cell wasDerivedFrom Natural_killer_cell?oldid=605108455.
- Natural_killer_cell depiction HLA-Cw4.png.
- Natural_killer_cell isPrimaryTopicOf Natural_killer_cell.
