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- Nelarabine abstract "Nelarabine is a chemotherapy drug used in T-cell acute lymphoblastic leukemia. It was previously known as 506U78. Nelarabine is a purine nucleoside analog converted to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and cytotoxicity. Pre-clinical studies suggest that T-cells are particularly sensitive to nelarabine. In October 2005, it was approved by the FDA for T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma that has not responded to or has relapsed following treatment with at least two chemotherapy regimens. It was later approved in the European Union in the October of 2005. Complete responses have been achieved with this medication. It is marketed in the US as Arranon and as Atriance in the EU by GlaxoSmithKline.".
- Nelarabine atcPrefix "L01".
- Nelarabine atcSuffix "BB07".
- Nelarabine casNumber "121032-29-9".
- Nelarabine drugbank "DB01280".
- Nelarabine fdaUniiCode "60158CV180".
- Nelarabine iupacName "(2R,3S,4S,5R)-2-(2-amino-6-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol".
- Nelarabine pubchem "3011155".
- Nelarabine thumbnail Nelarabine_structure.svg?width=300.
- Nelarabine wikiPageID "1300692".
- Nelarabine wikiPageRevisionID "592269628".
- Nelarabine atcPrefix "L01".
- Nelarabine atcSuffix "BB07".
- Nelarabine bioavailability "n/a".
- Nelarabine c "11".
- Nelarabine casNumber "121032".
- Nelarabine chembl "1201112".
- Nelarabine chemspiderid "2280207".
- Nelarabine drugbank "DB01280".
- Nelarabine eliminationHalfLife "10800.0".
- Nelarabine eliminationHalfLife "1800.0".
- Nelarabine excretion Kidney.
- Nelarabine h "15".
- Nelarabine hasPhotoCollection Nelarabine.
- Nelarabine image "Nelarabine ball-and-stick.png".
- Nelarabine inchi "1".
- Nelarabine inchikey "IXOXBSCIXZEQEQ-UHTZMRCNBK".
- Nelarabine iupacName "-2".
- Nelarabine kegg "D05134".
- Nelarabine legalUs "Rx-only".
- Nelarabine licenceEu "Atriance".
- Nelarabine licenceUs "Nelarabine".
- Nelarabine metabolism "By adenosine deaminase, to 9-β-(D)-arabinofuranosylguanine".
- Nelarabine molecularWeight "297.268".
- Nelarabine n "5".
- Nelarabine o "5".
- Nelarabine pregnancyUs "D".
- Nelarabine proteinBound "<25%".
- Nelarabine pubchem "3011155".
- Nelarabine routesOfAdministration Intravenous_therapy.
- Nelarabine smiles "n2c1cn[C@@H]3O[C@@H]CO".
- Nelarabine stdinchi "1".
- Nelarabine stdinchikey "IXOXBSCIXZEQEQ-UHTZMRCNSA-N".
- Nelarabine unii "60158".
- Nelarabine verifiedfields "changed".
- Nelarabine verifiedrevid "461742367".
- Nelarabine watchedfields "changed".
- Nelarabine width "200".
- Nelarabine subject Category:Nucleosides.
- Nelarabine subject Category:Purine_antagonists.
- Nelarabine subject Category:Purines.
- Nelarabine type Abstraction100002137.
- Nelarabine type Base114618253.
- Nelarabine type Chemical114806838.
- Nelarabine type Compound114818238.
- Nelarabine type Glycoside114887305.
- Nelarabine type Material114580897.
- Nelarabine type Matter100020827.
- Nelarabine type Nucleoside114964367.
- Nelarabine type Nucleosides.
- Nelarabine type OrganicCompound114727670.
- Nelarabine type Part113809207.
- Nelarabine type PhysicalEntity100001930.
- Nelarabine type Purine114706749.
- Nelarabine type Purines.
- Nelarabine type Relation100031921.
- Nelarabine type Substance100019613.
- Nelarabine type Drug.
- Nelarabine type DrugProduct.
- Nelarabine type FunctionalSubstance.
- Nelarabine comment "Nelarabine is a chemotherapy drug used in T-cell acute lymphoblastic leukemia. It was previously known as 506U78. Nelarabine is a purine nucleoside analog converted to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and cytotoxicity. Pre-clinical studies suggest that T-cells are particularly sensitive to nelarabine.".
- Nelarabine label "Nelarabin".
- Nelarabine label "Nelarabina".
- Nelarabine label "Nelarabine".
- Nelarabine sameAs Nelarabin.
- Nelarabine sameAs Nelarabina.
- Nelarabine sameAs m.04r3bd.
- Nelarabine sameAs Q1216264.
- Nelarabine sameAs Q1216264.
- Nelarabine sameAs nelarabine.
- Nelarabine sameAs DB01280.
- Nelarabine sameAs 96312.
- Nelarabine sameAs Nelarabine.
- Nelarabine wasDerivedFrom Nelarabine?oldid=592269628.
- Nelarabine depiction Nelarabine_structure.svg.
- Nelarabine isPrimaryTopicOf Nelarabine.
