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- NrrF_RNA abstract "NrrF is a non-coding RNA which is regulated by the Ferric uptake regulator (Fur) protein in bacteria. This non-coding RNA was identified in Neisseria meningitidis and is involved in iron regulation of the succinate dehydrogenase genes sdhA and sdhC. NrrF acts as an antisense RNA and is complementary to the junction between the second and third genes of the sdh operon (sdhD and sdhA). Secondary structure predictions have indicated that this interaction occurs in a single stranded loop region of the NrrF RNA. Under low iron concentration NrrF is present at a high concentration and forms a duplex with the transcript in Hfq dependent manner. The RNA chaperone Hfq acts to enhance binding of NrrF or stabilizes the NrrF/sdh transcript duplex. Binding of NrrF results in down regulation of the sdhCDAB mRNA transcript results in a Fur-dependent positive regulation of succinate dehydrogenase.NrrF appears to be restricted to the Neisseria species and no homologues have yet been identified in other species.".
- NrrF_RNA thumbnail RF01416.png?width=300.
- NrrF_RNA wikiPageExternalLink RF01416.
- NrrF_RNA wikiPageID "23522814".
- NrrF_RNA wikiPageRevisionID "592675640".
- NrrF_RNA caption "Predicted secondary structure of NrrF RNA".
- NrrF_RNA hasPhotoCollection NrrF_RNA.
- NrrF_RNA name "NrrF RNA".
- NrrF_RNA rfam "RF01416".
- NrrF_RNA rnaType Antisense_RNA.
- NrrF_RNA rnaType Gene.
- NrrF_RNA symbol "NrrF".
- NrrF_RNA taxDomain Neisseria.
- NrrF_RNA width "200".
- NrrF_RNA subject Category:Non-coding_RNA.
- NrrF_RNA comment "NrrF is a non-coding RNA which is regulated by the Ferric uptake regulator (Fur) protein in bacteria. This non-coding RNA was identified in Neisseria meningitidis and is involved in iron regulation of the succinate dehydrogenase genes sdhA and sdhC. NrrF acts as an antisense RNA and is complementary to the junction between the second and third genes of the sdh operon (sdhD and sdhA).".
- NrrF_RNA label "NrrF RNA".
- NrrF_RNA sameAs m.06w88td.
- NrrF_RNA sameAs Q7067538.
- NrrF_RNA sameAs Q7067538.
- NrrF_RNA wasDerivedFrom NrrF_RNA?oldid=592675640.
- NrrF_RNA depiction RF01416.png.
- NrrF_RNA isPrimaryTopicOf NrrF_RNA.
