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- Nuclear_receptor abstract "In the field of molecular biology, nuclear receptors are a class of proteins found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules. In response, these receptors work with other proteins to regulate the expression of specific genes, thereby controlling the development, homeostasis, and metabolism of the organism.Nuclear receptors have the ability to directly bind to DNA and regulate the expression of adjacent genes, hence these receptors are classified as transcription factors. The regulation of gene expression by nuclear receptors generally only happens when a ligand — a molecule that affects the receptor's behavior — is present. More specifically, ligand binding to a nuclear receptor results in a conformational change in the receptor, which, in turn, activates the receptor, resulting in up-regulation or down-regulation of gene expression.A unique property of nuclear receptors that differentiates them from other classes of receptors is their ability to directly interact with and control the expression of genomic DNA. As a consequence, nuclear receptors play key roles in both embryonic development and adult homeostasis. As discussed below, nuclear receptors may be classified according to either mechanism or homology.".
- Nuclear_receptor symbol "Hormone_recep".
- Nuclear_receptor symbol "zf-C4".
- Nuclear_receptor thumbnail PPARg_RXRa_3E00.png?width=300.
- Nuclear_receptor wikiPageExternalLink nrrhome.htm.
- Nuclear_receptor wikiPageExternalLink index_nh.jsp.
- Nuclear_receptor wikiPageExternalLink www.nrresource.org.
- Nuclear_receptor wikiPageExternalLink www.nuclear-receptor.com.
- Nuclear_receptor wikiPageExternalLink www.nursa.org.
- Nuclear_receptor wikiPageID "6103321".
- Nuclear_receptor wikiPageRevisionID "603461218".
- Nuclear_receptor caption "Crystallographic structure of the human progesterone receptor DNA-binding domain dimer complexed with double strained DNA . Zinc atoms of are depicted as grey spheres.".
- Nuclear_receptor caption "Crystallographic structure of the ligand binding domain of the human RORγ complexed with 25-hydroxycholesterol".
- Nuclear_receptor cdd "cd06157".
- Nuclear_receptor cdd "cd06916".
- Nuclear_receptor colwidth "35".
- Nuclear_receptor hasPhotoCollection Nuclear_receptor.
- Nuclear_receptor interpro "IPR000536".
- Nuclear_receptor interpro "IPR001628".
- Nuclear_receptor name "DNA binding domain".
- Nuclear_receptor name "Ligand-binding domain".
- Nuclear_receptor pfam "PF00104".
- Nuclear_receptor pfam "PF00105".
- Nuclear_receptor prosite "PDOC00031".
- Nuclear_receptor scop "1".
- Nuclear_receptor smart "SM00399".
- Nuclear_receptor smart "SM00430".
- Nuclear_receptor symbol "Hormone_recep".
- Nuclear_receptor symbol "zf-C4".
- Nuclear_receptor subject Category:Intracellular_receptors.
- Nuclear_receptor subject Category:Protein_families.
- Nuclear_receptor subject Category:Transcription_factors.
- Nuclear_receptor type Abstraction100002137.
- Nuclear_receptor type Family108078020.
- Nuclear_receptor type Group100031264.
- Nuclear_receptor type Organization108008335.
- Nuclear_receptor type ProteinFamilies.
- Nuclear_receptor type SocialGroup107950920.
- Nuclear_receptor type Unit108189659.
- Nuclear_receptor type YagoLegalActor.
- Nuclear_receptor type YagoLegalActorGeo.
- Nuclear_receptor type YagoPermanentlyLocatedEntity.
- Nuclear_receptor type Biomolecule.
- Nuclear_receptor type Protein.
- Nuclear_receptor type BiologicalObject.
- Nuclear_receptor comment "In the field of molecular biology, nuclear receptors are a class of proteins found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules.".
- Nuclear_receptor label "Kernrezeptor".
- Nuclear_receptor label "Nuclear receptor".
- Nuclear_receptor label "Receptor nuclear".
- Nuclear_receptor label "Receptor nuclear".
- Nuclear_receptor label "Receptory jądrowe".
- Nuclear_receptor label "Recettore nucleare".
- Nuclear_receptor label "Récepteur nucléaire".
- Nuclear_receptor label "مستقبل نووي".
- Nuclear_receptor label "核内受容体".
- Nuclear_receptor label "核受体".
- Nuclear_receptor sameAs Kernrezeptor.
- Nuclear_receptor sameAs Receptor_nuclear.
- Nuclear_receptor sameAs Récepteur_nucléaire.
- Nuclear_receptor sameAs Recettore_nucleare.
- Nuclear_receptor sameAs 核内受容体.
- Nuclear_receptor sameAs Receptory_jądrowe.
- Nuclear_receptor sameAs Receptor_nuclear.
- Nuclear_receptor sameAs m.0fq8df.
- Nuclear_receptor sameAs Q422500.
- Nuclear_receptor sameAs Q422500.
- Nuclear_receptor sameAs Nuclear_receptor.
- Nuclear_receptor wasDerivedFrom Nuclear_receptor?oldid=603461218.
- Nuclear_receptor depiction PPARg_RXRa_3E00.png.
- Nuclear_receptor isPrimaryTopicOf Nuclear_receptor.
