Matches in DBpedia 2014 for { <http://dbpedia.org/resource/OAS2> ?p ?o. }
Showing items 1 to 21 of
21
with 100 items per page.
- OAS2 abstract "2'-5'-oligoadenylate synthetase 2 is an enzyme that in humans is encoded by the OAS2 gene.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.".
- OAS2 entrezgene "4939".
- OAS2 wikiPageID "14877872".
- OAS2 wikiPageRevisionID "592685032".
- OAS2 hasPhotoCollection OAS2.
- OAS2 requireManualInspection "no".
- OAS2 summaryText "This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates . These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.".
- OAS2 updateCitations "yes".
- OAS2 updatePage "yes".
- OAS2 updateProteinBox "yes".
- OAS2 updateSummary "yes".
- OAS2 type Biomolecule.
- OAS2 type Protein.
- OAS2 type BiologicalObject.
- OAS2 comment "2'-5'-oligoadenylate synthetase 2 is an enzyme that in humans is encoded by the OAS2 gene.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As).".
- OAS2 label "OAS2".
- OAS2 sameAs m.03g__hg.
- OAS2 sameAs Q7072290.
- OAS2 sameAs Q7072290.
- OAS2 wasDerivedFrom OAS2?oldid=592685032.
- OAS2 isPrimaryTopicOf OAS2.