Matches in DBpedia 2014 for { <http://dbpedia.org/resource/ORC2> ?p ?o. }
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- ORC2 abstract "Origin recognition complex subunit 2 is a protein that in humans is encoded by the ORC2 (ORC2L) gene.The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, ORC4, and ORC5. It also interacts with CDC45L and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication.".
- ORC2 entrezgene "4999".
- ORC2 symbol "ORC2".
- ORC2 wikiPageID "14760114".
- ORC2 wikiPageRevisionID "592714387".
- ORC2 hasPhotoCollection ORC2.
- ORC2 interpro "IPR007220".
- ORC2 name "Origin recognition complex subunit 2".
- ORC2 pfam "PF04084".
- ORC2 requireManualInspection "no".
- ORC2 summaryText "The origin recognition complex is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, ORC4, and ORC5. It also interacts with CDC45L and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication.".
- ORC2 symbol "ORC2".
- ORC2 updateCitations "yes".
- ORC2 updatePage "yes".
- ORC2 updateProteinBox "yes".
- ORC2 updateSummary "yes".
- ORC2 type Biomolecule.
- ORC2 type Protein.
- ORC2 type BiologicalObject.
- ORC2 comment "Origin recognition complex subunit 2 is a protein that in humans is encoded by the ORC2 (ORC2L) gene.The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins.".
- ORC2 label "ORC2".
- ORC2 sameAs m.03gx00g.
- ORC2 sameAs Q7072906.
- ORC2 sameAs Q7072906.
- ORC2 wasDerivedFrom ORC2?oldid=592714387.
- ORC2 isPrimaryTopicOf ORC2.