Matches in DBpedia 2014 for { <http://dbpedia.org/resource/OSTM1> ?p ?o. }
Showing items 1 to 28 of
28
with 100 items per page.
- OSTM1 abstract "Osteopetrosis-associated transmembrane protein 1 is a protein that in humans is encoded by the OSTM1 gene. It is required for osteoclast and melanocyte maturation and function.This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. This is also known as autosomal recessive Albers-Schonberg disease.The OSTM1 gene is regulated by the Microphthalmia-associated transcription factor.".
- OSTM1 entrezgene "28962".
- OSTM1 symbol "OSTMP1".
- OSTM1 wikiPageID "15070946".
- OSTM1 wikiPageRevisionID "592723328".
- OSTM1 hasPhotoCollection OSTM1.
- OSTM1 interpro "IPR019172".
- OSTM1 name "Osteopetrosis-associated transmembrane protein 1 precursor".
- OSTM1 pfam "PF09777".
- OSTM1 requireManualInspection "no".
- OSTM1 summaryText "This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. This is also known as autosomal recessive Albers-Schonberg disease. The OSTM1 gene is regulated by the Microphthalmia-associated transcription factor.".
- OSTM1 symbol "OSTMP1".
- OSTM1 updateCitations "yes".
- OSTM1 updatePage "yes".
- OSTM1 updateProteinBox "yes".
- OSTM1 updateSummary "yes".
- OSTM1 subject Category:Protein_families.
- OSTM1 type Biomolecule.
- OSTM1 type Protein.
- OSTM1 type BiologicalObject.
- OSTM1 comment "Osteopetrosis-associated transmembrane protein 1 is a protein that in humans is encoded by the OSTM1 gene. It is required for osteoclast and melanocyte maturation and function.This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region.".
- OSTM1 label "OSTM1".
- OSTM1 sameAs m.03hgkjv.
- OSTM1 sameAs Q7073055.
- OSTM1 sameAs Q7073055.
- OSTM1 sameAs OSTM1.
- OSTM1 wasDerivedFrom OSTM1?oldid=592723328.
- OSTM1 isPrimaryTopicOf OSTM1.