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- Optogenetics abstract "Optogenetics (from Greek optos, meaning "visible") uses light to control neurons which have been genetically sensitised to light. It is a neuromodulation technique employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied in the lab of Gero Miesenböck, now Waynflete Professor of Physiology at the University of Oxford, and Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behavior.In 2010, optogenetics was chosen as the Method of the Year across all fields of science and engineering by the interdisciplinary research journal Nature Methods (Primer on Optogenetics, EditorialCommentary). At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the scientific research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.".
- Optogenetics thumbnail Example_of_optogenetic_activation_of_prefrontal_cortex.jpg?width=300.
- Optogenetics wikiPageExternalLink sohal.html.
- Optogenetics wikiPageExternalLink S0092-8674(08)00215-8.
- Optogenetics wikiPageExternalLink S0165-0270(09)00080-6.
- Optogenetics wikiPageExternalLink S0896-6273(06)00176-0.
- Optogenetics wikiPageExternalLink S0896-6273(07)00183-3.
- Optogenetics wikiPageExternalLink S0896-6273(07)00344-3.
- Optogenetics wikiPageExternalLink S0896-6273(09)00210-4.
- Optogenetics wikiPageExternalLink S0959-4388(07)00121-3.
- Optogenetics wikiPageExternalLink S0960-9822(08)00959-7.
- Optogenetics wikiPageExternalLink neurocloud.org.
- Optogenetics wikiPageExternalLink nurmikko.engin.brown.edu.
- Optogenetics wikiPageExternalLink x48167.xml.
- Optogenetics wikiPageExternalLink syntheticneurobiology.org.
- Optogenetics wikiPageExternalLink 2010-award.
- Optogenetics wikiPageExternalLink pmidlookup?view=long&pmid=18614669.
- Optogenetics wikiPageExternalLink pmidlookup?view=long&pmid=19005051.
- Optogenetics wikiPageExternalLink pan.htm.
- Optogenetics wikiPageExternalLink nmeth.f.321.html.
- Optogenetics wikiPageExternalLink nmeth.f.323.html.
- Optogenetics wikiPageExternalLink nmeth.f.324.html.
- Optogenetics wikiPageExternalLink www.neurocloud.org.
- Optogenetics wikiPageExternalLink www.openoptogenetics.org.
- Optogenetics wikiPageExternalLink www.openoptogeneticsblog.org.
- Optogenetics wikiPageExternalLink pmidlookup?view=long&pmid=17170269.
- Optogenetics wikiPageExternalLink article.cfm?id=optogenetics-controlling.
- Optogenetics wikiPageExternalLink optogenetics.
- Optogenetics wikiPageExternalLink research.html.
- Optogenetics wikiPageExternalLink optophysiology.
- Optogenetics wikiPageExternalLink watch?v=I64X7vHSHOE.
- Optogenetics wikiPageID "14958673".
- Optogenetics wikiPageRevisionID "603119343".
- Optogenetics hasPhotoCollection Optogenetics.
- Optogenetics subject Category:Biological_techniques_and_tools.
- Optogenetics subject Category:Brain–computer_interfacing.
- Optogenetics subject Category:Control_theory.
- Optogenetics subject Category:Cybernetics.
- Optogenetics subject Category:Neural_engineering.
- Optogenetics subject Category:Neuroprosthetics.
- Optogenetics subject Category:Neuroscience.
- Optogenetics type Ability105616246.
- Optogenetics type Abstraction100002137.
- Optogenetics type BiologicalTechniquesAndTools.
- Optogenetics type Cognition100023271.
- Optogenetics type Know-how105616786.
- Optogenetics type Method105660268.
- Optogenetics type PsychologicalFeature100023100.
- Optogenetics type Technique105665146.
- Optogenetics comment "Optogenetics (from Greek optos, meaning "visible") uses light to control neurons which have been genetically sensitised to light. It is a neuromodulation technique employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time.".
- Optogenetics label "Optogenetica".
- Optogenetics label "Optogenetics".
- Optogenetics label "Optogenetik".
- Optogenetics label "Optogenetyka".
- Optogenetics label "Optogenética".
- Optogenetics label "Optogenética".
- Optogenetics label "Optogénétique".
- Optogenetics label "Оптогенетика".
- Optogenetics label "علم البصريات الوراثي".
- Optogenetics label "光遺伝学".
- Optogenetics label "光遺傳學".
- Optogenetics sameAs Optogenetik.
- Optogenetics sameAs Optogenética.
- Optogenetics sameAs Optogénétique.
- Optogenetics sameAs Optogenetica.
- Optogenetics sameAs 光遺伝学.
- Optogenetics sameAs Optogenetyka.
- Optogenetics sameAs Optogenética.
- Optogenetics sameAs m.03h2_gt.
- Optogenetics sameAs Q781492.
- Optogenetics sameAs Q781492.
- Optogenetics sameAs Optogenetics.
- Optogenetics wasDerivedFrom Optogenetics?oldid=603119343.
- Optogenetics depiction Example_of_optogenetic_activation_of_prefrontal_cortex.jpg.
- Optogenetics isPrimaryTopicOf Optogenetics.
