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- Orexigenic abstract "An orexigenic, or appetite stimulant, is a drug, hormone, or compound that increases appetite. This can be a naturally occurring neuropeptide hormone such as ghrelin, orexin or neuropeptide Y, or a medication which increases hunger and therefore enhances food consumption. Usually appetite enhancement is considered an undesirable side effect of certain drugs as it leads to unwanted weight gain, but sometimes it can be beneficial and a drug may be prescribed solely for this purpose, especially when the patient is suffering from severe appetite loss or muscle wasting due to cystic fibrosis, anorexia, old age, cancer or AIDS. There are several widely used drugs which can cause a boost in appetite, including tricyclic antidepressants (TCAs), tetracyclic antidepressants, natural or synthetic cannabinoids, first-generation antihistamines, most antipsychotics and many steroid hormones.Agents with orexigenic effects include the following: 5-HT2C receptor antagonists/inverse agonists — mirtazapine, olanzapine, quetiapine, amitriptyline, cyproheptadine H1 receptor antagonists/inverse agonists — mirtazapine, olanzapine, quetiapine, amitriptyline, cyproheptadine Dopamine antagonists — haloperidol, chlorpromazine, olanzapine, risperidone, quetiapine Adrenergic antagonists — carvedilol, propranolol; α2-adrenergic antagonists — mirtazapine; α2-adrenergic agonists – clonidine CB1 receptor agonists (cannabinoids — THC/dronabinol (a component of Cannabis), nabilone Corticosteroids — dexamethasone, prednisone, hydrocortisone Certain pregnene steroids — megestrol acetate, medroxyprogesterone acetate Anabolic steroids — oxandrolone, nandrolone, testosterone Sulfonylurea antidiabetic drugs — glibenclamide and chlorpropamide α2δ VDCC ligands — pregabalin Insulin↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑ ↑".
- Orexigenic wikiPageExternalLink www.appetitestimulants.org.
- Orexigenic wikiPageID "23832994".
- Orexigenic wikiPageRevisionID "595657881".
- Orexigenic hasPhotoCollection Orexigenic.
- Orexigenic subject Category:Drugs.
- Orexigenic type Agent114778436.
- Orexigenic type CausalAgent100007347.
- Orexigenic type Drug103247620.
- Orexigenic type Drugs.
- Orexigenic type Matter100020827.
- Orexigenic type PhysicalEntity100001930.
- Orexigenic type Substance100020090.
- Orexigenic comment "An orexigenic, or appetite stimulant, is a drug, hormone, or compound that increases appetite. This can be a naturally occurring neuropeptide hormone such as ghrelin, orexin or neuropeptide Y, or a medication which increases hunger and therefore enhances food consumption.".
- Orexigenic label "Oressizzante".
- Orexigenic label "Orexigenic".
- Orexigenic label "Orexígeno".
- Orexigenic sameAs Orexígeno.
- Orexigenic sameAs Oressizzante.
- Orexigenic sameAs m.06_v6fc.
- Orexigenic sameAs Q433807.
- Orexigenic sameAs Q433807.
- Orexigenic sameAs Orexigenic.
- Orexigenic wasDerivedFrom Orexigenic?oldid=595657881.
- Orexigenic isPrimaryTopicOf Orexigenic.