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- Org_12,962 abstract "Org 12,962 is a drug developed by Organon, which acts as a potent and selective agonist for the 5-HT2 receptor family, with highest affinity at 5-HT2C and lowest at 5-HT2B subtypes. It was developed as a potential anti-anxiety drug, but was discontinued from human trials after tests in a public speaking challenge showed that its anti-anxiety effects were accompanied by side effects such as dizziness and a "spacey" feeling, which were attributed to poor selectivity in vivo over the hallucinogenic 5-HT2A receptor.".
- Org_12,962 casNumber "210821-63-9".
- Org_12,962 iupacName "1-(5-trifluoromethyl-6-chloropyridin-2-yl)piperazine".
- Org_12,962 pubchem "9796408".
- Org_12,962 thumbnail Org12962_structure.png?width=300.
- Org_12,962 wikiPageID "30849835".
- Org_12,962 wikiPageRevisionID "592716535".
- Org_12,962 c "10".
- Org_12,962 casNumber "210821".
- Org_12,962 chembl "506999".
- Org_12,962 chemspiderid "7972174".
- Org_12,962 cl "1".
- Org_12,962 f "3".
- Org_12,962 h "11".
- Org_12,962 hasPhotoCollection Org_12,962.
- Org_12,962 iupacName "1".
- Org_12,962 legalStatus "Uncontrolled".
- Org_12,962 molecularWeight "265.662".
- Org_12,962 n "3".
- Org_12,962 pubchem "9796408".
- Org_12,962 smiles "C2CNCCN2cccc1CF".
- Org_12,962 stdinchi "1".
- Org_12,962 stdinchikey "QZYYPQAYSFBKPW-UHFFFAOYSA-N".
- Org_12,962 verifiedfields "changed".
- Org_12,962 verifiedrevid "462265658".
- Org_12,962 width "240".
- Org_12,962 subject Category:Piperazines.
- Org_12,962 subject Category:Serotonin_receptor_agonists.
- Org_12,962 type Drug.
- Org_12,962 type FunctionalSubstance.
- Org_12,962 comment "Org 12,962 is a drug developed by Organon, which acts as a potent and selective agonist for the 5-HT2 receptor family, with highest affinity at 5-HT2C and lowest at 5-HT2B subtypes.".
- Org_12,962 label "Org 12,962".
- Org_12,962 sameAs m.0gfjl0r.
- Org_12,962 sameAs Q7101734.
- Org_12,962 sameAs Q7101734.
- Org_12,962 wasDerivedFrom Org_12,962?oldid=592716535.
- Org_12,962 depiction Org12962_structure.png.
- Org_12,962 isPrimaryTopicOf Org_12,962.