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- Orosomucoid abstract "Orosomucoid (ORM) or alpha-1-acid glycoprotein (AGP or AAG) is an acute phase (acute phase protein) plasma alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6-1.2 mg/mL (1-3% plasma protein). Plasma levels are affected by pregnancy, certain drugs, and certain diseases, particularly HIV.The only established function of ORM is to act as a carrier of basic and neutrally charged lipophilic compounds. In medicine, it is known as the primary carrier of basic drugs (whereas albumin carries acidic drugs), steroids, and protease inhibitors. Aging causes a small decrease in plasma albumin levels; if anything, there is a small increase in alpha-1-acid glycoprotein. The effect of these changes on drug protein binding and drug delivery, however, appear to be minimal.Alpha-1-acid glycoprotein has been identified as one of four potentially useful circulating biomarkers for estimating the five-year risk of all-cause mortality (the other three are albumin, very low-density lipoprotein particle size, and citrate).Orosomucoid increases in amount in obstructive jaundices while diminishes in hepatocellular jaundice and in intestinal infections.".
- Orosomucoid arm "q".
- Orosomucoid band "31".
- Orosomucoid chromosome "9".
- Orosomucoid entrezgene "5004".
- Orosomucoid entrezgene "5005".
- Orosomucoid hgncid "8498".
- Orosomucoid hgncid "8499".
- Orosomucoid locusSupplementaryData "-qter".
- Orosomucoid omim "138600".
- Orosomucoid omim "138610".
- Orosomucoid refseq "NM_000607".
- Orosomucoid refseq "NM_000608".
- Orosomucoid symbol "ORM1".
- Orosomucoid symbol "ORM2".
- Orosomucoid uniprot "P02763".
- Orosomucoid uniprot "P19652".
- Orosomucoid wikiPageID "7362120".
- Orosomucoid wikiPageRevisionID "604628260".
- Orosomucoid arm "q".
- Orosomucoid band "31".
- Orosomucoid chromosome "9".
- Orosomucoid entrezgene "5004".
- Orosomucoid entrezgene "5005".
- Orosomucoid hasPhotoCollection Orosomucoid.
- Orosomucoid hgncid "8498".
- Orosomucoid hgncid "8499".
- Orosomucoid locussupplementarydata "-qter".
- Orosomucoid name ORM1.
- Orosomucoid name "orosomucoid 2".
- Orosomucoid omim "138600".
- Orosomucoid omim "138610".
- Orosomucoid refseq "NM_000607".
- Orosomucoid refseq "NM_000608".
- Orosomucoid symbol ORM1.
- Orosomucoid symbol "ORM2".
- Orosomucoid uniprot "P02763".
- Orosomucoid uniprot "P19652".
- Orosomucoid subject Category:Acute_phase_proteins.
- Orosomucoid subject Category:Glycoproteins.
- Orosomucoid subject Category:Molecular_biology.
- Orosomucoid subject Category:Proteomics.
- Orosomucoid type Abstraction100002137.
- Orosomucoid type AcutePhaseProteins.
- Orosomucoid type Chemical114806838.
- Orosomucoid type Compound114818238.
- Orosomucoid type ConjugatedProtein114731135.
- Orosomucoid type Glycoprotein114888310.
- Orosomucoid type Glycoproteins.
- Orosomucoid type Macromolecule114944888.
- Orosomucoid type Material114580897.
- Orosomucoid type Matter100020827.
- Orosomucoid type Molecule114682133.
- Orosomucoid type OrganicCompound114727670.
- Orosomucoid type Part113809207.
- Orosomucoid type PhysicalEntity100001930.
- Orosomucoid type Protein114728724.
- Orosomucoid type Relation100031921.
- Orosomucoid type Substance100019613.
- Orosomucoid type Thing100002452.
- Orosomucoid type Unit109465459.
- Orosomucoid type Biomolecule.
- Orosomucoid type Protein.
- Orosomucoid type ProteinMolecule.
- Orosomucoid type BiologicalObject.
- Orosomucoid comment "Orosomucoid (ORM) or alpha-1-acid glycoprotein (AGP or AAG) is an acute phase (acute phase protein) plasma alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6-1.2 mg/mL (1-3% plasma protein).".
- Orosomucoid label "Alfa 1-glicoproteina acida".
- Orosomucoid label "Orosomucoid".
- Orosomucoid label "Orosomucoïde".
- Orosomucoid sameAs Orosomukoid.
- Orosomucoid sameAs Orosomucoïde.
- Orosomucoid sameAs Alfa_1-glicoproteina_acida.
- Orosomucoid sameAs m.025_b39.
- Orosomucoid sameAs Q2628787.
- Orosomucoid sameAs Q2628787.
- Orosomucoid sameAs Orosomucoid.
- Orosomucoid wasDerivedFrom Orosomucoid?oldid=604628260.
- Orosomucoid isPrimaryTopicOf Orosomucoid.
- Orosomucoid name "orosomucoid 1".
- Orosomucoid name "orosomucoid 2".