Matches in DBpedia 2014 for { <http://dbpedia.org/resource/P53_upregulated_modulator_of_apoptosis> ?p ?o. }
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- P53_upregulated_modulator_of_apoptosis abstract "The p53 upregulated modulator of apoptosis (PUMA) also known as Bcl-2-binding component 3 (BBC3), is a pro-apoptotic protein, member of the Bcl-2 protein family. In humans, the Bcl-2-binding component 3 protein is encoded by the BBC3 gene.The expression of PUMA is regulated by the tumor suppressor p53. PUMA is involved in p53-dependent and -independent apoptosis induced by a variety of signals, and is regulated by transcription factors, not by post-translational modifications. After activation, PUMA interacts with antiapoptotic Bcl-2 family members, thus freeing Bax and/or Bak which are then able to signal apoptosis to the mitochondria. Following mitochondrial dysfunction, the caspase cascade is activated ultimately leading to cell death.".
- P53_upregulated_modulator_of_apoptosis entrezgene "27113".
- P53_upregulated_modulator_of_apoptosis wikiPageID "7856684".
- P53_upregulated_modulator_of_apoptosis wikiPageRevisionID "592732739".
- P53_upregulated_modulator_of_apoptosis hasPhotoCollection P53_upregulated_modulator_of_apoptosis.
- P53_upregulated_modulator_of_apoptosis subject Category:Apoptosis.
- P53_upregulated_modulator_of_apoptosis subject Category:Programmed_cell_death.
- P53_upregulated_modulator_of_apoptosis subject Category:Proteins.
- P53_upregulated_modulator_of_apoptosis type Biomolecule.
- P53_upregulated_modulator_of_apoptosis type Protein.
- P53_upregulated_modulator_of_apoptosis type ProteinMolecule.
- P53_upregulated_modulator_of_apoptosis type BiologicalObject.
- P53_upregulated_modulator_of_apoptosis comment "The p53 upregulated modulator of apoptosis (PUMA) also known as Bcl-2-binding component 3 (BBC3), is a pro-apoptotic protein, member of the Bcl-2 protein family. In humans, the Bcl-2-binding component 3 protein is encoded by the BBC3 gene.The expression of PUMA is regulated by the tumor suppressor p53. PUMA is involved in p53-dependent and -independent apoptosis induced by a variety of signals, and is regulated by transcription factors, not by post-translational modifications.".
- P53_upregulated_modulator_of_apoptosis label "P53 upregulated modulator of apoptosis".
- P53_upregulated_modulator_of_apoptosis sameAs m.026ggcb.
- P53_upregulated_modulator_of_apoptosis sameAs Q14907288.
- P53_upregulated_modulator_of_apoptosis sameAs Q14907288.
- P53_upregulated_modulator_of_apoptosis wasDerivedFrom P53_upregulated_modulator_of_apoptosis?oldid=592732739.
- P53_upregulated_modulator_of_apoptosis isPrimaryTopicOf P53_upregulated_modulator_of_apoptosis.