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- PABPC4 abstract "Polyadenylate-binding protein 4 is a protein that in humans is encoded by the PABPC4 gene.Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules.".
- PABPC4 entrezgene "8761".
- PABPC4 wikiPageID "14815981".
- PABPC4 wikiPageRevisionID "592733035".
- PABPC4 hasPhotoCollection PABPC4.
- PABPC4 requireManualInspection "no".
- PABPC4 summaryText "--05-04".
- PABPC4 updateCitations "yes".
- PABPC4 updatePage "yes".
- PABPC4 updateProteinBox "yes".
- PABPC4 updateSummary "yes".
- PABPC4 subject Category:Genes_mutated_in_mice.
- PABPC4 type Biomolecule.
- PABPC4 type Protein.
- PABPC4 type BiologicalObject.
- PABPC4 comment "Polyadenylate-binding protein 4 is a protein that in humans is encoded by the PABPC4 gene.Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus.".
- PABPC4 label "PABPC4".
- PABPC4 sameAs m.03gyxm0.
- PABPC4 sameAs Q7118023.
- PABPC4 sameAs Q7118023.
- PABPC4 wasDerivedFrom PABPC4?oldid=592733035.
- PABPC4 isPrimaryTopicOf PABPC4.