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- PACRG abstract "Parkin coregulated gene protein is a protein that in humans is encoded by the PACRG gene.This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.".
- PACRG entrezgene "135138".
- PACRG wikiPageID "14817248".
- PACRG wikiPageRevisionID "592734092".
- PACRG hasPhotoCollection PACRG.
- PACRG requireManualInspection "no".
- PACRG summaryText "This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.".
- PACRG updateCitations "yes".
- PACRG updatePage "yes".
- PACRG updateProteinBox "yes".
- PACRG updateSummary "yes".
- PACRG type Biomolecule.
- PACRG type Protein.
- PACRG type BiologicalObject.
- PACRG comment "Parkin coregulated gene protein is a protein that in humans is encoded by the PACRG gene.This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy.".
- PACRG label "PACRG".
- PACRG sameAs m.03gyz6z.
- PACRG sameAs Q7118048.
- PACRG sameAs Q7118048.
- PACRG wasDerivedFrom PACRG?oldid=592734092.
- PACRG isPrimaryTopicOf PACRG.