Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PADI2> ?p ?o. }
Showing items 1 to 22 of
22
with 100 items per page.
- PADI2 abstract "Protein-arginine deiminase type-2 is an enzyme that in humans is encoded by the PADI2 gene.This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.".
- PADI2 entrezgene "11240".
- PADI2 wikiPageID "14876741".
- PADI2 wikiPageRevisionID "592734423".
- PADI2 hasPhotoCollection PADI2.
- PADI2 requireManualInspection "no".
- PADI2 summaryText "This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.".
- PADI2 updateCitations "yes".
- PADI2 updatePage "yes".
- PADI2 updateProteinBox "yes".
- PADI2 updateSummary "yes".
- PADI2 type Biomolecule.
- PADI2 type Protein.
- PADI2 type BiologicalObject.
- PADI2 comment "Protein-arginine deiminase type-2 is an enzyme that in humans is encoded by the PADI2 gene.This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member.".
- PADI2 label "PADI2".
- PADI2 sameAs m.03g_y96.
- PADI2 sameAs Q15996985.
- PADI2 sameAs Q15996985.
- PADI2 sameAs 4068.
- PADI2 wasDerivedFrom PADI2?oldid=592734423.
- PADI2 isPrimaryTopicOf PADI2.