Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PAK7> ?p ?o. }
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- PAK7 abstract "Serine/threonine-protein kinase PAK 7 is an enzyme that in humans is encoded by the PAK7 gene.The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.".
- PAK7 entrezgene "57144".
- PAK7 wikiPageID "14814788".
- PAK7 wikiPageRevisionID "592735797".
- PAK7 hasPhotoCollection PAK7.
- PAK7 requireManualInspection "no".
- PAK7 summaryText "The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.".
- PAK7 updateCitations "yes".
- PAK7 updatePage "yes".
- PAK7 updateProteinBox "yes".
- PAK7 updateSummary "yes".
- PAK7 type Biomolecule.
- PAK7 type Protein.
- PAK7 type BiologicalObject.
- PAK7 comment "Serine/threonine-protein kinase PAK 7 is an enzyme that in humans is encoded by the PAK7 gene.The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP.".
- PAK7 label "PAK7".
- PAK7 sameAs m.03gyw41.
- PAK7 sameAs Q7118124.
- PAK7 sameAs Q7118124.
- PAK7 wasDerivedFrom PAK7?oldid=592735797.
- PAK7 isPrimaryTopicOf PAK7.