Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PAWR> ?p ?o. }
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- PAWR abstract "PRKC, apoptosis, WT1, regulator, also known as PAWR or Prostate apoptosis response-4 (Par-4), is a human gene coding for a tumor-suppressor protein that induces apoptosis in cancer cells, but not in normal cells.The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.The active domain of the Par-4 protein has been found to confer cancer resistance in transgenic mice without compromising normal viability or aging, and may have therapeutic significance.".
- PAWR entrezgene "5074".
- PAWR wikiPageID "14171528".
- PAWR wikiPageRevisionID "606607798".
- PAWR hasPhotoCollection PAWR.
- PAWR requireManualInspection "no".
- PAWR summaryText "The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.".
- PAWR updateCitations "yes".
- PAWR updatePage "yes".
- PAWR updateProteinBox "yes".
- PAWR updateSummary "yes".
- PAWR type Biomolecule.
- PAWR type Protein.
- PAWR type BiologicalObject.
- PAWR comment "PRKC, apoptosis, WT1, regulator, also known as PAWR or Prostate apoptosis response-4 (Par-4), is a human gene coding for a tumor-suppressor protein that induces apoptosis in cancer cells, but not in normal cells.The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor.".
- PAWR label "PAWR".
- PAWR sameAs m.03cws4q.
- PAWR sameAs Q7118309.
- PAWR sameAs Q7118309.
- PAWR wasDerivedFrom PAWR?oldid=606607798.
- PAWR isPrimaryTopicOf PAWR.