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- PCDHA9 abstract "Protocadherin alpha-9 is a protein that in humans is encoded by the PCDHA9 gene.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome 5 that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.".
- PCDHA9 entrezgene "9752".
- PCDHA9 wikiPageID "15227493".
- PCDHA9 wikiPageRevisionID "592757929".
- PCDHA9 hasPhotoCollection PCDHA9.
- PCDHA9 requireManualInspection "no".
- PCDHA9 summaryText "This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome 5 that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.".
- PCDHA9 updateCitations "yes".
- PCDHA9 updatePage "yes".
- PCDHA9 updateProteinBox "yes".
- PCDHA9 updateSummary "yes".
- PCDHA9 type Biomolecule.
- PCDHA9 type Protein.
- PCDHA9 type BiologicalObject.
- PCDHA9 comment "Protocadherin alpha-9 is a protein that in humans is encoded by the PCDHA9 gene.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome 5 that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences.".
- PCDHA9 label "PCDHA9".
- PCDHA9 sameAs m.03hml29.
- PCDHA9 sameAs Q7118545.
- PCDHA9 sameAs Q7118545.
- PCDHA9 wasDerivedFrom PCDHA9?oldid=592757929.
- PCDHA9 isPrimaryTopicOf PCDHA9.