Matches in DBpedia 2014 for { <http://dbpedia.org/resource/PCDHAC2> ?p ?o. }
Showing items 1 to 21 of
21
with 100 items per page.
- PCDHAC2 abstract "Protocadherin alpha-C2 is a protein that in humans is encoded by the PCDHAC2 gene.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.".
- PCDHAC2 entrezgene "56134".
- PCDHAC2 wikiPageID "16853889".
- PCDHAC2 wikiPageRevisionID "592757943".
- PCDHAC2 hasPhotoCollection PCDHAC2.
- PCDHAC2 requireManualInspection "no".
- PCDHAC2 summaryText "This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.".
- PCDHAC2 updateCitations "yes".
- PCDHAC2 updatePage "yes".
- PCDHAC2 updateProteinBox "yes".
- PCDHAC2 updateSummary "yes".
- PCDHAC2 type Biomolecule.
- PCDHAC2 type Protein.
- PCDHAC2 type BiologicalObject.
- PCDHAC2 comment "Protocadherin alpha-C2 is a protein that in humans is encoded by the PCDHAC2 gene.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.".
- PCDHAC2 label "PCDHAC2".
- PCDHAC2 sameAs m.0408g96.
- PCDHAC2 sameAs Q7118546.
- PCDHAC2 sameAs Q7118546.
- PCDHAC2 wasDerivedFrom PCDHAC2?oldid=592757943.
- PCDHAC2 isPrimaryTopicOf PCDHAC2.