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- PCDHB12 abstract "Protocadherin beta-12 is a protein that in humans is encoded by the PCDHB12 gene.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.".
- PCDHB12 entrezgene "56124".
- PCDHB12 wikiPageID "16853841".
- PCDHB12 wikiPageRevisionID "592757978".
- PCDHB12 hasPhotoCollection PCDHB12.
- PCDHB12 requireManualInspection "no".
- PCDHB12 summaryText "This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.".
- PCDHB12 updateCitations "yes".
- PCDHB12 updatePage "yes".
- PCDHB12 updateProteinBox "yes".
- PCDHB12 updateSummary "yes".
- PCDHB12 type Biomolecule.
- PCDHB12 type Protein.
- PCDHB12 type BiologicalObject.
- PCDHB12 comment "Protocadherin beta-12 is a protein that in humans is encoded by the PCDHB12 gene.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.".
- PCDHB12 label "PCDHB12".
- PCDHB12 sameAs m.0408g85.
- PCDHB12 sameAs Q15997003.
- PCDHB12 sameAs Q15997003.
- PCDHB12 wasDerivedFrom PCDHB12?oldid=592757978.
- PCDHB12 isPrimaryTopicOf PCDHB12.