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- PCDHB14 abstract "Protocadherin beta-14 is a protein that in humans is encoded by the PCDHB14 gene.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.".
- PCDHB14 entrezgene "56122".
- PCDHB14 wikiPageID "15220865".
- PCDHB14 wikiPageRevisionID "592757988".
- PCDHB14 hasPhotoCollection PCDHB14.
- PCDHB14 requireManualInspection "no".
- PCDHB14 summaryText "This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.".
- PCDHB14 updateCitations "yes".
- PCDHB14 updatePage "yes".
- PCDHB14 updateProteinBox "yes".
- PCDHB14 updateSummary "yes".
- PCDHB14 type Biomolecule.
- PCDHB14 type Protein.
- PCDHB14 type BiologicalObject.
- PCDHB14 comment "Protocadherin beta-14 is a protein that in humans is encoded by the PCDHB14 gene.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.".
- PCDHB14 label "PCDHB14".
- PCDHB14 sameAs m.03hmbds.
- PCDHB14 sameAs Q15997006.
- PCDHB14 sameAs Q15997006.
- PCDHB14 wasDerivedFrom PCDHB14?oldid=592757988.
- PCDHB14 isPrimaryTopicOf PCDHB14.