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- PCDHB2 abstract "Protocadherin beta-2 is a protein that in humans is encoded by the PCDHB2 gene.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.".
- PCDHB2 entrezgene "56133".
- PCDHB2 wikiPageID "15220915".
- PCDHB2 wikiPageRevisionID "592758020".
- PCDHB2 hasPhotoCollection PCDHB2.
- PCDHB2 requireManualInspection "no".
- PCDHB2 summaryText "This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.".
- PCDHB2 updateCitations "yes".
- PCDHB2 updatePage "yes".
- PCDHB2 updateProteinBox "yes".
- PCDHB2 updateSummary "yes".
- PCDHB2 type Biomolecule.
- PCDHB2 type Protein.
- PCDHB2 type BiologicalObject.
- PCDHB2 comment "Protocadherin beta-2 is a protein that in humans is encoded by the PCDHB2 gene.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.".
- PCDHB2 label "PCDHB2".
- PCDHB2 sameAs m.03hmbgv.
- PCDHB2 sameAs Q7118555.
- PCDHB2 sameAs Q7118555.
- PCDHB2 wasDerivedFrom PCDHB2?oldid=592758020.
- PCDHB2 isPrimaryTopicOf PCDHB2.