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- PCDHB3 abstract "Protocadherin beta-3 is a protein that in humans is encoded by the PCDHB3 gene.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.".
- PCDHB3 entrezgene "56132".
- PCDHB3 wikiPageID "16853883".
- PCDHB3 wikiPageRevisionID "592758031".
- PCDHB3 hasPhotoCollection PCDHB3.
- PCDHB3 requireManualInspection "no".
- PCDHB3 summaryText "This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.".
- PCDHB3 updateCitations "yes".
- PCDHB3 updatePage "yes".
- PCDHB3 updateProteinBox "yes".
- PCDHB3 updateSummary "yes".
- PCDHB3 type Biomolecule.
- PCDHB3 type Protein.
- PCDHB3 type BiologicalObject.
- PCDHB3 comment "Protocadherin beta-3 is a protein that in humans is encoded by the PCDHB3 gene.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.".
- PCDHB3 label "PCDHB3".
- PCDHB3 sameAs m.0408g8w.
- PCDHB3 sameAs Q7118556.
- PCDHB3 sameAs Q7118556.
- PCDHB3 wasDerivedFrom PCDHB3?oldid=592758031.
- PCDHB3 isPrimaryTopicOf PCDHB3.