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- PCDHB4 abstract "Protocadherin beta-4 is a protein that in humans is encoded by the PCDHB4 gene.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.".
- PCDHB4 entrezgene "56131".
- PCDHB4 wikiPageID "15352832".
- PCDHB4 wikiPageRevisionID "592758036".
- PCDHB4 hasPhotoCollection PCDHB4.
- PCDHB4 requireManualInspection "no".
- PCDHB4 summaryText "This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.".
- PCDHB4 updateCitations "yes".
- PCDHB4 updatePage "yes".
- PCDHB4 updateProteinBox "yes".
- PCDHB4 updateSummary "yes".
- PCDHB4 type Biomolecule.
- PCDHB4 type Protein.
- PCDHB4 type BiologicalObject.
- PCDHB4 comment "Protocadherin beta-4 is a protein that in humans is encoded by the PCDHB4 gene.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.".
- PCDHB4 label "PCDHB4".
- PCDHB4 sameAs m.03m5yvw.
- PCDHB4 sameAs Q7118557.
- PCDHB4 sameAs Q7118557.
- PCDHB4 wasDerivedFrom PCDHB4?oldid=592758036.
- PCDHB4 isPrimaryTopicOf PCDHB4.