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- PCDHB7 abstract "Protocadherin beta-7 is a protein that in humans is encoded by the PCDHB7 gene.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. The transcript for this particular family member uses more than one polyadenylation site.".
- PCDHB7 entrezgene "56129".
- PCDHB7 wikiPageID "15352537".
- PCDHB7 wikiPageRevisionID "592758063".
- PCDHB7 hasPhotoCollection PCDHB7.
- PCDHB7 requireManualInspection "no".
- PCDHB7 summaryText "This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. The transcript for this particular family member uses more than one polyadenylation site.".
- PCDHB7 updateCitations "yes".
- PCDHB7 updatePage "yes".
- PCDHB7 updateProteinBox "yes".
- PCDHB7 updateSummary "yes".
- PCDHB7 type Biomolecule.
- PCDHB7 type Protein.
- PCDHB7 type BiologicalObject.
- PCDHB7 comment "Protocadherin beta-7 is a protein that in humans is encoded by the PCDHB7 gene.This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.".
- PCDHB7 label "PCDHB7".
- PCDHB7 sameAs m.03m5ym9.
- PCDHB7 sameAs Q7118559.
- PCDHB7 sameAs Q7118559.
- PCDHB7 wasDerivedFrom PCDHB7?oldid=592758063.
- PCDHB7 isPrimaryTopicOf PCDHB7.