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- PCDHGC3 abstract "Protocadherin gamma-C3 is a protein that in humans is encoded by the PCDHGC3 gene.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.".
- PCDHGC3 entrezgene "5098".
- PCDHGC3 wikiPageID "15063009".
- PCDHGC3 wikiPageRevisionID "592758108".
- PCDHGC3 hasPhotoCollection PCDHGC3.
- PCDHGC3 requireManualInspection "no".
- PCDHGC3 summaryText "This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.".
- PCDHGC3 updateCitations "yes".
- PCDHGC3 updatePage "yes".
- PCDHGC3 updateProteinBox "yes".
- PCDHGC3 updateSummary "yes".
- PCDHGC3 type Biomolecule.
- PCDHGC3 type Protein.
- PCDHGC3 type BiologicalObject.
- PCDHGC3 comment "Protocadherin gamma-C3 is a protein that in humans is encoded by the PCDHGC3 gene.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies.".
- PCDHGC3 label "PCDHGC3".
- PCDHGC3 sameAs m.03hg6__.
- PCDHGC3 sameAs Q16252621.
- PCDHGC3 sameAs Q16252621.
- PCDHGC3 wasDerivedFrom PCDHGC3?oldid=592758108.
- PCDHGC3 isPrimaryTopicOf PCDHGC3.