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- PD-L1 abstract "Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene.Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. Normally the immune system reacts to foreign antigens where there is some accumulation in the lymph nodes or spleen which triggers a proliferation of antigen-specific CD8+ T cell. The formation of PD-1 receptor / PD-L1 or B7.1 receptor /PD-L1 ligand complex transmits an inhibitory signal which reduces the proliferation of these CD8+ T cells at the lymph nodes and supplementary to that PD-1 is also able to control the accumulation of foreign antigen specific T cells in the lymph nodes through apoptosis which is further mediated by a lower regulation of the gene Bcl-2.".
- PD-L1 entrezgene "29126".
- PD-L1 thumbnail B7_family_ligands_and_CD28_family_receptors.JPG?width=300.
- PD-L1 wikiPageID "14157278".
- PD-L1 wikiPageRevisionID "603540954".
- PD-L1 hasPhotoCollection PD-L1.
- PD-L1 requireManualInspection "no".
- PD-L1 updateCitations "yes".
- PD-L1 updatePage "yes".
- PD-L1 updateProteinBox "yes".
- PD-L1 updateSummary "yes".
- PD-L1 subject Category:Clusters_of_differentiation.
- PD-L1 type Biomolecule.
- PD-L1 type Protein.
- PD-L1 type BiologicalObject.
- PD-L1 comment "Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene.Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis.".
- PD-L1 label "PD-L1".
- PD-L1 label "細胞程式死亡-配體1".
- PD-L1 sameAs m.03cw9h1.
- PD-L1 sameAs Q7118744.
- PD-L1 sameAs Q7118744.
- PD-L1 wasDerivedFrom PD-L1?oldid=603540954.
- PD-L1 depiction B7_family_ligands_and_CD28_family_receptors.JPG.
- PD-L1 isPrimaryTopicOf PD-L1.