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- PDGFRB abstract "Beta-type platelet-derived growth factor receptor is a protein that in humans is encoded by the PDGFRB gene.This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5q- syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.".
- PDGFRB entrezgene "5159".
- PDGFRB wikiPageID "14076099".
- PDGFRB wikiPageRevisionID "602075659".
- PDGFRB hasPhotoCollection PDGFRB.
- PDGFRB requireManualInspection "no".
- PDGFRB summaryText "This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5q- syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.".
- PDGFRB updateCitations "yes".
- PDGFRB updatePage "yes".
- PDGFRB updateProteinBox "yes".
- PDGFRB updateSummary "yes".
- PDGFRB subject Category:Clusters_of_differentiation.
- PDGFRB type Abstraction100002137.
- PDGFRB type Agglomeration107959269.
- PDGFRB type Bunch107959943.
- PDGFRB type ClustersOfDifferentiation.
- PDGFRB type Collection107951464.
- PDGFRB type Group100031264.
- PDGFRB type Biomolecule.
- PDGFRB type Protein.
- PDGFRB type BiologicalObject.
- PDGFRB comment "Beta-type platelet-derived growth factor receptor is a protein that in humans is encoded by the PDGFRB gene.This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin.".
- PDGFRB label "PDGFRB".
- PDGFRB sameAs m.03cstbn.
- PDGFRB sameAs Q7118817.
- PDGFRB sameAs Q7118817.
- PDGFRB sameAs PDGFRB.
- PDGFRB sameAs 228.
- PDGFRB sameAs PDGFRB.
- PDGFRB wasDerivedFrom PDGFRB?oldid=602075659.
- PDGFRB isPrimaryTopicOf PDGFRB.